纯净水加氯化钠在洗胃中的临床应用  

The clinical application of pure water and sodium chloride in gastric lavage

作　　者：罗天玉[1] 张红梅[1] 陈凤玲[1] 马小萍[1] 夏秋江[2,3] 王青丽[2,3] 张希洲[2,3] 

机构地区：[1]枝江市人民医院急诊科,湖北宜昌443200 [2]湖北省宜昌市第一人民医院 [3]三峡大学人民医院急诊科

出　　处：《临床急诊杂志》2013年第3期125-127,共3页Journal of Clinical Emergency

基　　金：宜昌市计划课题(No:A01301-27)

摘　　要：目的:观察纯净水加氯化钠在口服药物中毒中的临床应用效果。方法:将248例口服中毒患者随机分为观察组(127例)和对照组(121例)。对照组以纯净水洗胃,观察组以纯净水加氯化钠(每桶纯净水10L加氯化钠90g,相当于0.9%氯化钠)洗胃,两组均用自制特殊加温装置加热到36℃。观察洗胃前后的平均动脉压、心率、血常规、血钠和血钾情况,并留剩余洗胃液送培养。结果:洗胃后两组血清钠浓度、平均动脉压水平的差异有统计学意义(P<0.01)。剩余洗胃液送培养结果,对照组大肠杆菌超标,观察未见超标大肠杆菌生长。结论:纯净水水源充足,符合饮用水卫生标准,加入一定量的氯化钠后,接近生理盐水的浓度,能避免洗胃时出现的低钠血症及血压下降现象,减少院内交叉感染。Objective：The clinical application of pure water and sodium chloride in gastric lavage of oral drug poisoning patients. Method.. Two hundred and forty-eight oral drug poisoning patients were divided into the obser- vation group （127 cases） and the control group （121 cases） randomly. 36℃ clean water was used for gastric lavage in the control group. The observation group had gastric lavage with 36℃ pure water and sodium chloride（a barrel of pure water 10 L with sodium chloride 90 g,as much as 0.9~ sodium chloride）. The water was heated to 36℃ with homemade special warming device. The mean arterial pressure, heart rate,hemogram, blood sodium and potas- sium during gastric lavage were observed and gastric juice was sent to culture. Result.. There were significant differences （P〈0.01）in the concentration of serum sodium,mean arterial pressure level between the two groups. The culture results showed that the E. Coli was overproof in control group,while there was no overproof in the ob- servation group. Conclusion.. Purified water is abundant,and meet the drinking water health standards. It is close to the concentration of the physiological saline with a certain amount of sodium chloride. It can avoid hyponatremia and the fall of blood pressure after gastric lavage in oral drug poisoning patients,and reduce cross infection.

关 键 词：口服药物中毒 洗胃 洗胃液 纯净水 氯化钠 

分 类 号：R595.4[医药卫生—内科学]