血液透析患者不宁腿综合征的患病率及相关因素分析  

Prevalence and Correlation Factors Analysis of Restless Legs Syndrome in Hemodialysis Patients

作　　者：沈炜娣[1] 干静[1] 魏雅荣[1] 吴谷奋[2] 陆玮[2] 任肖玉[1] 蒋更如[2] 刘振国[1] 

机构地区：[1]上海交通大学医学院附属新华医院神经内科,200092 [2]上海交通大学医学院附属新华医院肾脏内科,200092

出　　处：《中国临床神经科学》2013年第2期133-137,共5页Chinese Journal of Clinical Neurosciences

基　　金：国家自然科学基金资助项目(编号:81171204);上海市卫生局青年科研项目(编号:2010Y049);院级青年科研项目(编号:12QYJ08)

摘　　要：目的调查血液透析患者中不宁腿综合征(RLS)的患病率,了解相关影响因素对睡眠、生活质量的影响。方法对194例血液透析患者进行横断面调查,采用匹兹堡睡眠质量指数量表(PSQI)、健康状况调查简表(SF-36)对睡眠和生活质量进行评估。结果 194例血液透析患者分为:RLS组31例和无RLS组163例。RLS患病率为16.0%。RLS组与无RLS组在年龄、性别、透析时间及生化指标等方面比较,均差异无统计学意义。RLS组睡眠质量与无RLS组比较,差异有统计学意义(P=0.000);生活质量比较差异无统计学意义。结论伴有RLS的血液透析患者睡眠质量明显下降,与RLS严重程度有关,对患者生活质量无明显影响。Aim To evaluate the prevalence of restless legs syndrome （RLS） in hemodialysis patients, analyze the potential correlated factors of RLS, and assess its impact on patients＇ sleep disturbances and the quality of life. Methods 194 patients with the hemodialysis were studied, collecting the data of general information and biochemical parameters, evaluating the quality of sleep and life. Independent-samples t test, Chi-aquare test and linear correlation were employed. Results The prevalence of RLS of hemodialysis patients in our blood decontamination room was 16.0%. There were no significant differences in age, gender, duration of hemodialysis, biochemical parameters and the quality of life between the patients with RLS and without RLS. The Pittsburgh Sleep Quality Index （PSQI） of patients with RLS was higher than those without RLS （P=0.000）. Conclusion The prevalence of RLS in hemodialysis patients in our blood decontamination room was 16.0%. The patients with RLS had a poorer quality of sleep, the RLS severity made an impact on the overall sleep quality, duration of sleep, sleep efficiency and day dysfunction due to sleepiness. The quality of life between the patients with RLS and those without RLS was similar.

关 键 词：血液透析 不宁腿综合征 患病率 睡眠质量 生活质量 

分 类 号：R459.5[医药卫生—治疗学]