单股正链RNA病毒基因组非编码区结构与功能研究进展  

PROGRESS IN THE RESEARCH ON STRUCTURE AND FUNCTION OF THE NON-CODING REGIONS OF POSITIVE-STRANDED RNA VIRUSES

作　　者：哲名家[1] 陈宗艳[1] 李传峰[1] 刘光清[1] 

机构地区：[1]中国农业科学院上海兽医研究所,上海200241

出　　处：《中国动物传染病学报》2012年第4期79-86,共8页Chinese Journal of Animal Infectious Diseases

摘　　要：单股正链RNA病毒基因组末端的非编码区(non-coding region,NCR)不仅参与RNA-RNA间相互作用,还可以通过与反式作用因子(trans-acting factor)结合,发挥对病毒基因组的复制、转录和组装等过程的调控作用。本文对近年来一些关于单股正链RNA病毒基因组非编码区的结构与功能研究进展情况进行综述。The non-coding regions （NCRs） of positive-stranded RNA viruses are involved in the interaction between RNA and RNA/or protein. They also play important roles in the regulation of viral genome replication, transcription and assembly by binding some trans- acting factors. This review focuses on recent progress in the research on structure and function of NCRs.

关 键 词：单股正链RNA病毒 非编码区 结构 功能 

分 类 号：S852.659.6[农业科学—基础兽医学]