连续性血液净化在治疗糖尿病乳酸酸中毒的临床研究  

Clinical Study of Continuous Blood Purification in Treatment of Diabetic Lactic Acidosis

作　　者：陈晓玲[1] 王洪武[1] 柏林[1] 

机构地区：[1]江苏省淮安市第二人民医院肾脏内科,223002

出　　处：《中华全科医学》2013年第5期722-723,共2页Chinese Journal of General Practice

摘　　要：目的观察连续性血液净化(CRRT)在治疗糖尿病乳酸酸中毒的应用疗效。方法回顾性分析2008年6月-2011年5月笔者所在医院行连续性血液净化抢救的重症糖尿病乳酸酸中毒患者12例,收集患者首次CRRT前后血生化、全血乳酸、血pH值的变化,统计患者的病死率及并发症。结果 12例患者抢救成功9例,死亡3例,病死率为25%。治疗后血pH值,HCO3-接近正常,血乳酸、血肌酐显著下降。结论连续性血液净化在抢救乳酸酸中毒的治疗中发挥重要作用,大大提高抢救的成功率,并发症少,能改善患者的预后,值得在临床上推广。Objective To observe the efficacy of continuous blood purification（ CBP）/continuous renal replacement therapy （CRRP） in the treatment of diabetic lactic acidosis. Methods The clinical data of 12 patients with severe diabetes lactic acidosis undergoing continuous blood purification in our hospital from June 2008 to May 2011 were analyzed retrospectively. The blood biochemical indices tests, whole blood lactate level, PH in blood, mortality of patients and complications were recorded before and after the first CRRT. Results Nine of twelve patients got successful rescue,three cases died and the mortality rate was 25 %. After the treatment, blood pH value and HCO3 - got normal, and the levels of blood lactate and creatinine decreased significantly. Conclusion Continuous blood purification can play a major role in the rescue of patients with lactic acidosis,it can improve the success rate of rescue, decrease the incidence of complications,improve the prognosis of patients, and is worth promotion in clinical practice.

关 键 词：连续性血液净化 乳酸酸中毒 糖尿病 

分 类 号：R459.52[医药卫生—治疗学] R587.1[医药卫生—临床医学]