从脾辨治慢性荨麻疹临床研究  

Clinical Observation for Treating Chronic Urticaria Based on Spleen Differentiation

作　　者：张翠月[1] 高征[2] 刘银伟[1] 

机构地区：[1]南阳理工学院张仲景国医学院,河南南阳473004 [2]南阳医学高等专科学校,河南南阳473061

出　　处：《中国实验方剂学杂志》2013年第8期298-301,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察从脾辨治慢性荨麻疹(CU)临床疗效。方法:采用前瞻性自身对照法进行研究,对符合诊断要求的72例患者从脾辨证分型,并给予相应治疗方药。其中脾虚湿蕴证CU治以益气健脾、除湿止痒;脾肺气虚证CU治以补益脾肺、疏风止痒;心脾气血两虚证CU治以益气健脾、补血养心、祛风止痒。分别以参苓白术散、玉屏风散、归脾汤为主加减组方而治之。观察各证型治疗前后临床表现、停药后复发情况以及副作用。结果:经治疗后,各型均获满意疗效,其中脾虚湿盛证总有效率为92.31%,脾肺气虚证总有效率91.67%,心脾气血两虚证总有效率为90.91%,三型比较,疗效无统计学差异。2个月的跟踪随访,结果复发共5例,其中脾虚湿蕴证2例,脾肺气虚证1例,心脾气血两虚证2例,三型无显著差异。从血、尿常规、肝、肾功等方面观察均未发现异常或不良反应。结论:从脾辨证分型论治慢性荨麻疹,疗效显著,且复发率低,毒副作用小,安全性高,值得临床进一步探究、推广。Objective：To observe the effect of treating chronic urticarial（CU） based on spleen differentiation.Method：This prospective,noncomparative interventional case series observed 72 patients with CU which were divided into three groups based on spleen differentiation：the group with deficiency of spleen（group 1） was given modified Shenling Baizhu San,the group with Qi deficiency of spleen and lungs（group 2） was given modified Yupingfeng San,and the group with deficiency of heart and spleen syndrome（group 3） was given modified Guipi Tang.Items such as changes in clinical symptoms and signs,recurrence after treatment,and side effects were examined.Result：After the treatment,satisfactory effects showed that total efficacy rate of group 1 was 92.31%,group 2 was 91.67%,group 3 was 90.91%.No significant deviation between the groups was found.And after 2 month follow-up for the cured patients,2 patients in group 1 showed relapse,and 1 in group 2,2 in group 3.So,no significant deviation was found for relapse.There were no side effect or abnormal phenomenon was found on the items of blood routine,urine routine,liver function and kidney function as well.Conclusion：Treating chronic urticarial based on spleen differentiation is a safe and effective therapeutic procedure,which is worth the further study and clinical application.

关 键 词：慢性荨麻疹 从脾辨治 临床观察 

分 类 号：R287[医药卫生—中药学]