基于数据库的平性药组方配伍规律研究  

Study on Compatibility Law of Chinese Herbs with Neutral-nature Based on the Data Base

作　　者：邓家刚[1] 孙冰[2] 郝二伟[1] 韩海荣[2] 张丽[2] 胡申[2] 

机构地区：[1]广西中医药大学,南宁350001 [2]济宁医学院,山东济宁272067

出　　处：《中国实验方剂学杂志》2013年第8期347-349,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家重点基础研究发展计划(973)项目(2007CB512602);山东省中医药科技发展计划项目(2009-179)

摘　　要：目的:通过分析1 307首古今方剂的药性组方规律,探讨了平性药组方配伍用药规律。方法:从国家规划教材《方剂学》及《中国药典》(以下简称《药典》)中筛选1 307首方剂,并以《药典》等为药性的判定依据,将获得的数据录入自创的"中药方剂药性数据分析系统",分析探讨平性药组方配伍规律,并以平性药分别作为君、臣、佐、使的应用频次上限10%确定为该组方角色常用药物,频次上限25%定为该组方角色主干药物。结果:不同药性在1 307首方剂中作为君臣佐使的频次统计:寒性、平性、热性药物,作君药者分别占42%,15%,43%,作臣药者分别占40%,17%,43%,作佐药者分别占37%,20%,43%;作使药者分别占17%,66%,17%;筛选出平性药作为君、臣、佐、使的常用药物及主干药物。结论:平性药在组方配伍方面有两大特点,一是少为君臣,重在和合;二是多为佐使,调和辅助;本研究方法所筛选出的君臣佐使常用平性药和主干平性药,将为临床组方用药及研究提供有益的参考。Objective：By analyzing the used law of different nature herbs in 1 307 prescriptions,research the compatibility law of chinese herbs with neutral-nature.Method：Screened 1 307 prescriptions from two books,science of prescription,and Pharmacopoeia of the People＇s Republic of China,judged the nature of herbs according to Pharmacopoeia,established the data base with the obtained data named Data analysis system of Chinese heabs and prescription.Research the compatibility law of chinese herbs with neutral-nature with the data base,defined the common heabs whose used frequency was upper limit 10% actored as sovereign,minister,assistant and courier,and defined the major herbs whose used frequency was upper limit 25%.Result：It is the used frequencies of heabs with different nature used as different actors in 1 307 prescriptions,that cold 42%,neutral 15%,hot 43% separately used as sovereign heab,cold 40%,neutral 17%,hot 43% separately used as minister heab,cold 37%,neutral 20%,hot 43% separately used as assistant heab,and cold 17%,neutral 66%,hot 17% separately used as assistant courier heab.Screened the common and major heabs with nentral nature used as sovereign,minister,assistant and courier.Conclusion：The feature of heab with neutral nature in compatibility.is less used as sovereign,minister heabs,more used as assistant and courier heabs.The screened commoned and majored heabs with neutral nature will provide a useful reference.

关 键 词：中药 平性药 数据库 组方配伍 

分 类 号：R287.6[医药卫生—中药学]