丙型肝炎病毒受体研究进展  

Progress in Research of HCV Receptors

作　　者：刘艳芝[1,2] 金敏[2] 李君文[1,2] 

机构地区：[1]中南大学公共卫生学院,湖南长沙410000 [2]军事医学科学院卫生学环境医学研究所天津市环境与食品安全风险监控技术重点实验室,天津300050

出　　处：《生物技术通讯》2013年第2期271-275,共5页Letters in Biotechnology

摘　　要：丙型肝炎病毒(HCV)入侵宿主细胞是在多种受体联合介导下才能完成的复杂过程。我们针对已报道的HCV可能的细胞受体CD81、低密度脂蛋白受体、B族Ⅰ型清道夫受体、紧密连接蛋白家族、表皮生长因子受体、酪氨酸激酶EphA2受体、NPC1L1受体展开介绍,为今后研究和探索新型HCV疫苗和药物奠定基础。The host cells invaded by hepatitis C virus（HCV） is such complicated process that can only be ac- complished under the mediation of various receptors. Some cell receptors reported may have some relations to HCV such as CD81, low density lipoprotein receptor, scavenger receptor class B type I, tight-junction proteins, epidermal growth factor receptor, Ephrin receptor A2, Niemann-Piek Cl-like 1 cholesterol absorption receptor. These thesis gives a detailed introduction of them, which could possibly make a foundation for searching new types of HCV vaccine and exploring antiviral medicine.

关 键 词：丙型肝炎病毒 受体 进展 

分 类 号：R373[医药卫生—病原生物学]