无创正压通气治疗COPD合并Ⅱ型呼吸衰竭的临床疗效分析  

作　　者：温晓雯[1] 

机构地区：[1]东莞市人民医院ICU,广东523059

出　　处：《当代医学》2013年第10期12-13,共2页Contemporary Medicine

摘　　要：目的探讨无创正压通气(NPPV)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的临床治疗效果。方法选择东莞市人民医院收治的106例COPD合并Ⅱ型呼吸衰竭患者为研究对象,随机分为治疗组和对照组,每组各53例,两组患者均行吸氧、抗感染、对症等常规治疗,治疗组在常规治疗的同时加用无创正压通气治疗,比较两组患者治疗前后的动脉血气和临床指标变化。结果两组患者治疗后pH、PaO2、PaCO2等血气指标均优于治疗前,差异具有统计学意义(P<0.05),治疗组比对照组改善更为明显(P<0.05);与对照组比较,治疗组的住院天数、插管率及病死率均下降或缩短,差异具有统计学意义(P<0.05)。结论 COPD合并Ⅱ型呼吸衰竭在常规治疗的同时加用NPPV可提高治疗效果,降低并发症的发生率和死亡率,值得临床推广应用。Objective To investigate the clinical curative effect of noninvasive positive pressure ventilation（NPPV） treatment of COPD combined Type Ⅱ respiratory failure. Methods 106 patients were randomly divided into treatment group and control group the 53 cases, two groups of patients were performed with oxygen, resistance to infection, suit and conventional treatment, the treatment group in the conventional treatment at the same time to add NPPV treatment, compared between the two groups before and after treatment in patients with the arterial blood gas and clinical indicators.Results Two groups of patients after treatment, the pH, PaO 2, PaCO 2 and gas indexes is better than the before treatment, the difference is statistically significant （P〈0.05）, the treatment group than the control group is more obvious improvement （P〈0.05）; Comparing with control group, the treatment group in days, intubation rate and mortality decreased or shorten, a statistically significant difference （P〈0.05）.Gonclusion COPD combined Type Ⅱ respiratory failure in the conventional treatment at the same time to add a NPPV can improve the treatment effect, to reduce the incidence of complications and mortality, it is worth clinical promotion.

关 键 词：无创正压通气 慢性阻塞性肺疾病 Ⅱ型呼吸衰竭 

分 类 号：R563.9[医药卫生—呼吸系统]