胎膜早破与新生儿感染的临床及病原菌分析  

Clinical analysis of pathogens causing infections in neonates with premature rupture of membranes

作　　者：刘艳[1] 郑晓明[1] 李小林[1] 王得玲[1] 

机构地区：[1]天津市第一中心医院妇产科,天津300192

出　　处：《中华医院感染学杂志》2013年第8期1848-1850,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析胎膜早破与新生儿感染的临床资料和病原菌分布。方法选取医院胎膜早破宫颈分泌物细菌培养阳性伴新生儿感染的孕妇40例为观察组,随机抽取同期胎膜早破宫颈分泌物细菌培养阳性但未出现新生儿感染的孕妇60例为对照组,对两组进行数据比较。结果观察组合并早产明显增多,占60.0%,对照组早产占25.0%;观察组破膜距分娩时间明显比对照组延长,差异有统计学意义(P<0.05);观察组宫颈分泌物与新生儿咽试子同时培养出革兰阳性球菌9株占22.5%,革兰阴性杆菌13株占32.5%,明显多于其他病原菌,差异有统计学意义(P<0.05)。结论应当注意病原菌检测,减少胎膜早破合并新生儿感染。OBJECTIVE To analyze the clinical data of the neonates with infections and premature rupture of membranes（PROM） as well as the distribution of pathogens.METHODS Forty cases of PROM with the positive result of cervical secretion germ culture and neonatal infections were selected as the study group,and sixty PROM cases matched for gestational age without neonatal infections as the control group.The etiological result and clinical data between the two groups were analyzed.The data of the two groups were compared.RESULTS Preterm delivery cases in the observation group increased significantly,accounting for 60.0%,while the preterm delivery cases in the control group accounted for 25.0%.The time from membrane rupture to delivery were significantly longer in the observation group than in the control group,the difference was statistically significant（P0.05）.In observation group,there were 9（22.5%） strains of gram-positive cocci and 13（32.5%） strains of gram-negative bacilli,which were isolated from the cervical secretions and the neonatal throat swab and were significantly more than other pathogens,the difference was statistically significant（P0.05）.CONCLUSION It is necessary to pay attention to the detection of the pathogens so as to reduce the incidence of the infections in the neonates with PROM.

关 键 词：胎膜早破 新生儿感染 病原菌 

分 类 号：R181.32[医药卫生—流行病学]