肉牛亚急性瘤胃酸中毒血液学及生化指标变化分析  

The changes of hematology and biochemical parameters in the beef cattle with subacute ruminal acidosis

作　　者：赵晨旭[1] 王晓旭[2] 孙国权[1,3] 张良[1] 陈灰[1] 杨文涛[1] 刘兆喜[1] 王哲[1] 刘国文[1] 

机构地区：[1]吉林大学动物医学学院,吉林长春130062 [2]军事医学科学院军事兽医研究所,吉林长春130122 [3]内蒙古民族大学动物科技学院,内蒙古通辽028000

出　　处：《中国兽医学报》2013年第4期604-607,共4页Chinese Journal of Veterinary Science

基　　金：国家自然科学基金资助项目(31072178;30600441)

摘　　要：为了解肉牛发生亚急性瘤胃酸中毒时血液学和相应生化指标的变化,对瘤胃液pH在5.2～5.5、5.6～5.8和5.9～6.8之间的24头肉牛进行了血液学及相应生化指标的分析。结果表明:随着pH值的降低,血液中红细胞(RBC)数量、血红蛋白(Hb)浓度、红细胞压积(PCV)均显著增加;白细胞(WBC)总数上升,白细胞分类(WBC-DC)也有相应的变化,嗜酸性粒细胞和淋巴细胞呈下降趋势,中性杆状核粒细胞和中性分叶核粒细胞呈上升趋势,单核细胞略微升高;血气指标pO2显著增加,pCO2、HCO3-浓度显著减少;生化指标Ca2+、Cl-显著减少,Na+和尿素氮显著增加,K+差异不显著。肉牛发生轻度和中度亚急性瘤胃酸中毒时,pCO2以及HCO3-含量显著降低,表明机体碱储备不足,缓冲能力下降,存在代偿性酸中毒;同时根据水合状态和血象指标,表明亚急性瘤胃酸中毒病牛存在轻度脱水和炎性反应。The aim of this study was to investigate the changes of hematology and biochemical pa- rameters in beef cattle with subacute ruminal acidosis. We analyzed the hematology and biochemical parameters of 24 beef cattle with ruminal pH value in 5.2-5.5,5.6-5.8 and 5.9-6.8. The results showed that red blood cell （RBC）, haemoglobin （Hb）, packed cell volume（PCV）significantly increased with the reducing pH value, the number of white blood cell（WBC）was increased. The leukocyte differential count was changed in the different degree, the proportion of eosinophilic leukocyte and lymphocyte was decreased,neutrophilic stab and segmented granulocyte was increased, mononuclear leucocyte was increased slightly. The pO2 was significantly increased. The pCO2 and HCO; were significantly decreased. The levels of Ca2＋ and Cl- were significantly decreased, the levels of Na＋ and urea nitrogen were significantly increased,and there was no Significant difference in the levels of K＋. The decreased pCO2 and HCO3- in the slight and moderate sick cattle indicate that the alkaline reserve was insufficient and the buffering capacity was reduced in the organism, thereby resulting in compensated acidosis. Mild dehydration and inflammatory reaction occurred in cattle with SARA.

关 键 词：肉牛 亚急性瘤胃酸中毒 血液学指标 生化指标 

分 类 号：S823.9[农业科学—畜牧学] S856.9[农业科学—畜牧兽医]