复发性尿路感染的细菌检验和药敏情况及治疗分析  

Bacteria Inspection and Drug Susceptibility Test and Analysis of Treatment of Recurrent Urinary Tract Infection

作　　者：简桂花[1] 贾平[2] 汪年松[1] 李军辉[1] 汤瑾[1] 

机构地区：[1]上海交通大学附属第六人民医院,上海200233 [2]复旦大学附属中山医院,上海200032

出　　处：《中国中西医结合肾病杂志》2013年第2期127-130,共4页Chinese Journal of Integrated Traditional and Western Nephrology

基　　金：国家自然基金面上项目(No.81270824);上海市国际科技合作基金资助项目(No.11410708500);上海市科委基金资助项目(No.114119a6100;11DZ1921904);上海市级医院新兴前沿技术攻关项目(No.SHDC12006101);上海市科委基础研究重大项目(No.11DJ1400101);上海市科委重大项目(No.11DZ1973103)

摘　　要：目的:分析复发性尿路感染的细菌检验和药敏对治疗影响并探讨治疗对策。方法:86例复发性尿路感染患者分析其尿细菌培养及药敏情况,并把患者分成培养阳性组和阴性组,分析对治疗的影响。采用分期长疗程治疗及根据尿细菌培养及敏感试验和临床验证选用抗生素,并观察其疗效。结果:86例患者中30例(34.9%)尿细菌培养阳性,其中大肠埃希菌24例(80%)。总治愈率为89.5%(77/86),治愈的26例细菌培养阳性组和51例细菌培养阴性组在治疗期、巩固期、维持期和总疗程方面均差异无统计学意义。共进行药敏试验587药次,能用于门诊作长疗程的口服药计137药次。口服药中敏感和中介的68药次中,临床表现敏感的仅58药次(9.88%)。结论:复发性尿路感染的尿细菌检验对指导长疗程治疗有局限性,应采用分期治疗方法、并根据药敏试验及临床验证方法选用抗生素。Objective： Analysis of bacteria and drug susceptibility test of recurrent urinary tract infection for treatment effect and discusses treatment countermeasures. Methods： Analysis of 86 cases of recurrent urinary tract infection patients with urinary bacte- rial culture and drug sensitive situation, And the patients into culture positive group and negative group, analysis the influence of the treatment. To employ installment long course of treatment and to choose antibiotics according to the urinary bacterial culture and sensi- tive test and clinical verification, and to observe its efficacy. Results： Among 86 patients, urine germiculture of 30 cases （34.9%） turned out positive, including 24 cases of escherichia coli （80%） . 77 cases（89.5% ） were cured. Cure patients 26 cases of germi- culture positive group and 51 cases of bacterial culture negative group in the treatment period, consolidate period, maintain period and total treatment are no statistical difference. A total of 587 medicine times of drug sensitive test, which can be used for oral agent 137 medicine outpatient program again, including test and the intermediary of medicine sensitive 68 times, clinical manifestations of sensi- tive only 58 medicine times （9.88%）. Conclusion：Because of urine culture and drug susceptibility limitations for Recurrent urinary tract infection, should according to antimicrobial susceptibility test and clinical verification method is used for antibiotics.

关 键 词：复发性尿路感染 分期治疗 细菌培养 药敏试验 

分 类 号：R446.5[医药卫生—诊断学]