老年高血压病合并冠心病的主动脉脉压、血清尿酸及踝臂指数的相关性研究  

Correlation research of aortic pulse pressure, serum uric acid and ankle-brachial index in elderly patients with coronary heart disease combined with hypertension

作　　者：王娜[1] 刘华玲[1] 

机构地区：[1]河南省周口市中心医院心血管内科,河南省周口市466100

出　　处：《中国实用医刊》2013年第7期4-6,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨老年高血压病合并冠心病的主动脉脉压、血清尿酸、踝臂指数的相关性。方法选择2010年8至2011年8月郑州大学第一附属医院收治住院的老年高血压痛合并冠心病排除相关疾病入组患者192例，依据冠状动脉64排CT结果分为：A组：单支血管病变（单支血管狭窄〉50％）47例；B组：双支血管病变（双支血管狭窄〉50％）52例；C组：三支血管病变（三支血管狭窄〉50％）48例。并与同期在我院体检中心体检无冠心病的单纯高血压病患者45例作为对照组（D组）。比较4组主动脉脉压、血清尿酸、踝臂指数之间的相关性。结果①与对照组比较，高血压病合并冠心病三组主动脉脉压与血尿酸高，踝臂指数低，差异有统计学意义（P均〈0．05）；高血压病合并冠心病三组间比较，三支冠状动脉病变与其他两组相比主动脉压与血尿酸高，踝臂指数低，差异有统计学意义（P均〈0．05）。双支冠状动脉病变与单支冠状动脉病变相比主动脉压与血尿酸高，踝臂指数低，差异均有统计学意义（P均〈0．05）。②高血压病合并冠心病三组中主动脉脉压与血尿酸水平呈正相关，与踝臂指数呈负相关。结论老年高血压病合并冠心病人群中，主动脉脉压和血尿酸呈正相关，随着冠状动脉病变严重程度的加重而增高；主动脉脉压和踝臂指数呈负相关，且随着冠状动脉病变严重程度的加重而降低。Objective To investigate the correlation of aortic pulse pressure, serum uric acid and ankle-brachial index in elderly patients with coronary heart disease combined with hypertension. Methods One hundred and ninety-two elderly patients with coronary heart disease combined with hypertension （exclude associated diseases） from August 2010 to August 2011 in the first affiliated hospital of Zhengzhou university were selected. Patients were divided into 3 groups accrording to the scanning result of 64 row CT. There were 47 cases of single vessel lesion （ single vessel stenosis 〉 50% ） in group A; 52 cases of double vessel disease（ double vessel stenosis 〉 50% ）in group B; 48 cases of three vessel lesions （three vessels stenosis 〉 50% ） in group C. They were compared with the controlled group （group D, 45 patients with hypertension and no coronary heart disease in the same period in the examination center. The correlation of aortic pulse pressure, serum uric acid and the ankle-brachial index were compared among the 4 groups. Results ①Compared with the controll group, the aortic pulse pressure and serum uric acid were high and the ankle brachial index was low in the three groups of coronary heart disease combined with hypertension （P 〈0.05） ; compared with the other two groups, the aortic pressure and serum uric acid in the three coronary artery disease were high and ankle-brachial index were low. The difference was statistically significant （P 〈 0. 05 ）. Compared with those of single coronary artery lesions, the indexes of aortic pressure and serum uric acid of double vessel disease were high, and the ankle-brachial index was low. The difference was statistically significant （P 〈 0. 05 ）. ②The aortic pulse pressure positively correlated with serum uric acid levels and negatively correlated with ankle-brachial index in the three groups of coronary heart disease combined with hypertension. Conclusions Elderly patients with coronary heart disease combined with hypertension in p

关 键 词：老年 高血压病 冠心病 主动脉脉压 血尿酸 踝臂指数 

分 类 号：R544.1[医药卫生—心血管疾病]