显微镜下多血管炎2例报告并文献复习  

Report of two cases of microscopic polyangiitis and literature review

作　　者：张嵩[1] 田东惠[2] 王新安[3] 

机构地区：[1]山东大学附属省立医院呼吸内科,济南250021, [2]滨州市人民医院神经内科,256610 [3]滨州市人民医院呼吸内科,256610

出　　处：《国际呼吸杂志》2013年第6期424-428,F0003,共6页International Journal of Respiration

摘　　要：目的探讨显微镜下多血管炎（MPA）肺部受累患者的临床特点，提高对MPA的认识和诊断水平。方法对我院确诊的2例MPA进行回顾性分析。结果2例患者均以肺部症状就诊，伴肾脏受累。p-ANCA阳性。经过激素、环磷酰胺治疗临床症状缓解。结论MPA临床表现无特异性，大多具有多脏器受累的特点，易误诊，ANCA对MPA的诊断有重要价值。激素及环磷酰胺联合治疗疗效佳。Objective To explore the clinical features of microscopic polyangiitis （MPA） complicated with pulmonary involvement in order to elevate realization about MPA and improve diagnositic level Methods Re-analyzing the two MPA cases in our hospital. Results Both of the two patients came with lung symptom, accompanied by involved kidney trouble. P-ANCA was positive, Symptomatic remission was acquired after the treatment with glucocorticoid combined cyclopbosphamide. Conclusions The clinical manifestation of MPA has no specificity, mostly accompanied by involved multiviscera trouble,being subject to misdiagnosis. Antineutrophil cytoplasmic antibody（ANCA）will be great value to MPA＇s diagnosis. Glucocorticoid combined cyclophosphamide is effective in the treatment of MPA.

关 键 词：显微镜下多血管炎 抗中性粒细胞胞浆抗体 血管炎 

分 类 号：R593.2[医药卫生—内科学]