不同粉碎方法对独活中蛇床子素和二氢欧芹醇当归酸酯含量测定的影响  

Effects of different grinding methods on the content of osthole and columbianctim in Angelicae Pubescentis Radix

作　　者：张亚中[1] 蒲婧哲 刘军玲[1] 袁杰[1] 翟宏焱[1] 班永生[1] 

机构地区：[1]安徽省食品药品检验所,安徽合肥230051

出　　处：《安徽医药》2013年第4期563-564,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的考察不同粉碎方法对独活中蛇床子素和二氢欧芹醇当归酸酯含量的影响。方法分别采用粉碎机和铜钵两种粉碎方法对独活进行粉碎处理,采用HPLC法测定其中蛇床子素和二氢欧芹醇当归酸酯的含量。结果不同粉碎方法处理的独活中两者含量差异很大,铜钵法处理的样品中蛇床子素的含量明显高于粉碎机处理的样品,而二氢欧芹醇当归酸酯的含量却有所降低。结论测定独活中蛇床子素和二氢欧芹醇当归酸酯的含量时,应采用铜钵粉碎。Objective To study the effects of different grinding methods on the content of osthole and columbianctim in Angelicae Pubes- centis Radix. Methods The content of osthole and columbianctim was detected in pulverizer grinding and copper bowl grinding sample by HPLC. Results The content of osthole and columbianctim in different grinding sample varied greatly. Osthole in copper bowl grinding sample was much higher than pulverizer grinding sample, but columbianctim was reduced. Conclusion The copper bowl grinding method should be used when we detect the content of osthole and columbianctim in Angelicae Pubescentis Radix.

关 键 词：独活 粉碎方法 蛇床子素 二氢欧芹醇当归酸酯 

分 类 号：R284.1[医药卫生—中药学]