婴幼儿重症肺炎PCT测定的临床研究  

The Clinical Study of the Detection of Procalcitonin in Infants and Young Children with Serious Pneumonia

作　　者：刘红霞[1] 王英宏[1] 邓永洪[1] 李小玲[1] 刘仁红[1] 肖毅[1] 

机构地区：[1]广州医学院附属深圳沙井医院,广东深圳518104

出　　处：《河北医学》2013年第5期663-666,共4页Hebei Medicine

基　　金：广东省深圳市宝安区科技局科研基金资助项目(项目编号:2012164)

摘　　要：目的:探讨PCT测定在婴幼儿重症肺炎中的临床意义。方法:选取重症肺炎75例,其中细菌性肺炎40例,病毒性肺炎25例,支原体肺炎10例,分别在急性期及恢复期给予PCT检测,并进行对比分析。结果:细菌性肺炎患儿PCT值显著高于病毒性肺炎及支原体肺炎患儿(P<0.05);病毒性肺炎患儿CRP显著低于细菌性与支原体性肺炎患儿(P<0.05);病毒性肺炎患儿WBC显著低于细菌性肺炎(P<0.01)。重症细菌性肺炎上述三项指标恢复期显著低于入院时(P<0.01)。结论:临床检测血清PCT值,有助于细菌性肺炎的早期诊断,并指导治疗。血清PCT浓度与婴幼儿肺炎严重程度呈正相关,同时可随病情的控制而逐渐降低,PCT可作为婴幼儿重症肺炎诊断、鉴别诊断、病情判断及预后评估的可靠指标。Objective： To discuss the clinical value of procalcitonin detection in infants and young children with serious pneumonia. Method： 75 cases of serious pneumonia, 40 cases bacterial pneumonia, and 25 cases uiral pneumonia were enrolled into the study, and all the children were given PCT detection, and then it was contrasted between the three groups. Result： PCTof the bacterial pneumonia was significantly higher than viral pneumonia and mycoplasma pneumonia （ P〈0.05 ） ; CRP of the viral pneumonia was significantly lower than of the bacterial pneumonia and the mycoplasma pneumonia （ P〈0.01 ） ; According to the PCT values from high to low arrangement in the bacterial pneumonia, they were respectively severe pneumonia group, mild pneumonia group, and the control group（ P〈0.05} ; PCT, WBC and CRP values in convalescence was significantly lower than before in the severe pneumonia group （ P〈0.01 ）. Conclusion： There is a positive correlation between PCT serum concentration and severity of the infants with pneumonia, PCT can be decreased as the disease controled, it can be used as areliable indicators in diagnosing, differential diagnosing, condition judgment and prognostic evaluation in infants and young children with severe pneumonia.

关 键 词：婴幼儿 重症肺炎 PCT 

分 类 号：R725.6[医药卫生—儿科]