介入导管与外周静脉溶栓治疗下肢深静脉血栓  

Catheter-directed and Peripheral Intravenous Thrombolytic Therapies for Lower Extremity Deep Vein Thrombosis

作　　者：严金林[1] 许中友[1] 马霁波[1] 祝慧鹏[1] 王辉[1] 童晓涛[1] 赵亲明[1] 

机构地区：[1]宁波大学医学院附属鄞州医院血管外科,宁波315000

出　　处：《中国中西医结合外科杂志》2013年第2期122-125,共4页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的:对比评价介入导管溶栓与外周静脉溶栓治疗下肢深静脉血栓的疗效。方法:对88例深静脉血栓病例分别行介入导管溶栓(44例)和外周静脉溶栓(44例),观察治疗前后下肢周径变化、血管通畅率以及并发症的发生率。结果:两组治疗后下肢周径均有显著缩小;住院期间、治疗后6个月、12个月血管通畅率,介入组优于外周组(P<0.05);介入组出血并发症高于外周组(P<0.01)。结论:介入导管溶栓治疗外周静脉血栓具有血栓溶解率高、远期通畅率高、操作简便、并发症少且可控等优点。Objective To comparatively evaluate the efficacy of catheter-directed and peripheral intrave?nous thrombolytic therapies for Lower extremity deep vein thrombosis. Methods Respectively application of cather-directed thrombolysis(44 cases) and peripheral intravenous thrombolysis (44 cases) were done in 88 pa?tients,to observe the lower extremity circumference change, blood vessel patency rate and complication incidenc?es before and after treatment. Results The lower limb circumferences were significantly reduced in both groups after treatment. During hospitalization, the 6 months,the 12 months after treatment, the blood vessel paten?cy rate in the intervention group was superior to the periphery group(P<0.05),bleeding-related complications in the intervention group was higher than the periphery group(P<0.01). Conclusion Catheter-directed throm?bolysis has the advantages of higher thrombolysis rate, higher long-term patency rate,simpler operation,fewer complications and controllability.

关 键 词：深静脉血栓 导管溶栓 尿激酶 肺栓塞 

分 类 号：R654.4[医药卫生—外科学]