健康成年新西兰兔肺动脉、肺静脉血流频谱分析及右心系统压力检测  

Doppler flow spectra analysis of pulmonary artery and vein and measurement of pulmonary artery pressure in healthy adult New Zealand rabbits

作　　者：孙丹丹[1,2] 段云友[1] 袁丽君[1] 陈洪茂[1] 梁宁南[1] 

机构地区：[1]第四军医大学唐都医院超声科,陕西西安710038 [2]吉林医药学院口腔影像系,吉林吉林132013

出　　处：《中国医学影像技术》2013年第4期489-492,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(81171349)

摘　　要：目的利用超声心动图及右心导管测量新西兰兔肺动脉、肺静脉频谱指标及右心系统压力指标,了解其频谱特点及右心系统压力的正常值范围。方法选择健康成年新西兰兔24只,用彩色多普勒超声诊断系统测量其肺动脉、肺静脉频谱,并同步记录心电图及呼吸曲线。通过右心导管记录并测量其右心房、右心室、肺动脉的收缩压及舒张压。结果频谱多普勒结果显示新西兰兔肺静脉频谱的峰值血流速度吸气相与呼气相的差异均无统计学意义(P均>0.05),肺动脉频谱峰值血流速度吸气相高于呼气相,差异有统计学意义(P<0.001)。右心导管压力测值结果显示新西兰兔肺动脉收缩压范围为16.07～23.99mmHg、肺动脉舒张压为11.18～19.22mmHg。结论超声心动图可清晰显示新西兰兔肺动脉、肺静脉血流;其肺动脉血流频谱随呼吸周期呈规律性变化。Objective To analyze the flow spectra of pulmonary artery （PA） and pulmonary vein （PV）, and to assess pressure of right atrium, right ventricum and PA using echocardiography and catheterization, so as to explore the normal ranges of the above indexes. Methods Twenty＇four healthy adult New Zealand rabbits were included. The flow velocities of PA and PV were measured with Doppler echocardiography, and the respiration curve and ECG were recorded simultane- ously. The pressure of PA, right atrium and ventricum were monitored using a pressure-guided microcatheter. Results There was no statistical difference in flow velocities of PV between inspiration and-expiration （all P〉0.05）. The peak val- ue of flow velocity of PA was higher during inspiration than expiration （P〈0. 001）. The measurement of right heart cathe ter showed that the reference range of PA systolic pressure of New Zealand rabbit was 16.07--23.99 mmHg, and of PA di- astolic pressure was 11.18--19.22 mmHg. Conclusion The flow spectra of PA and PV can be evaluated by echocardio graphy, and the flow spectra of PA varies with the respiratory cycle in New Zealand rabbits.

关 键 词：超声心动描记术 肺动脉 肺静脉 兔 

分 类 号：R332[医药卫生—人体生理学] R540.45[医药卫生—基础医学]