超声造影鉴别诊断子宫内膜良恶性病变  

Contrast-enhanced ultrasound in differential diagnosis of benign and malignant endometrial diseases

作　　者：王玲玲[1] 郑秀兰[1] 娄阁[2] 程文[1] 李海霞[1] 李洁冰[1] 

机构地区：[1]哈尔滨医科大学附属第三医院超声科,黑龙江哈尔滨150040 [2]哈尔滨医科大学附属第三医院妇科,黑龙江哈尔滨150040

出　　处：《中国医学影像技术》2013年第4期595-598,共4页Chinese Journal of Medical Imaging Technology

基　　金：黑龙江省卫生厅科研课题(2007405)

摘　　要：目的探讨CEUS时相及时间-强度曲线(TIC)鉴别诊断子宫内膜良恶性病变的价值。方法回顾性分析47例阴道不规则出血或排液患者,其中23例为子宫内膜癌(恶性组),24例为良性病变(良性组),分析其CEUS表现及TIC参数,并进行统计学比较。结果灌注时相:恶性组中52.17%(12/23)早于肌层灌注,47.83%(11/23)同步或晚于肌层灌注;良性组中16.67%(4/24)早于肌层灌注,83.33%(20/24)同步或晚于肌层灌注,二者差异具有统计学意义(P=0.028)。洗出时相:恶性组中82.61%(19/23)早于肌层洗出,良性组62.50%(15/24)早于肌层洗出,差异具有统计学意义(P=0.037)。良性组与恶性组子宫内膜的造影剂到达时间(AT)差异无统计学意义(P>0.05),达峰时间(TTP)及达峰强度(PI)的差异有统计学意义(P均<0.05)。结论子宫内膜良恶性病变的CEUS时相与TIC参数具有一定特征性,联合应用二者能够为临床提供丰富的信息,有助于鉴别良恶性子宫内膜病变。Objective To explore the value of CEUS and time-intensity curve （TIC） in differential diagnosis of benign and malignant endometria diseases. Methods Forty-seven patients with irregular vaginal bleeding and discharge including 23 endometrial carcinoma （malignant group） and 24 endometrial benign lesions （benign group） confirmed by pathology were analyzed retrospectively. The findings of CEUS and parameters of TIC were analyzed. Results Compared to myometrium, 52.17% （12/23） endometrial carcinoma showed earlier wash-in and 47.83% （11/23） showed same or later wash-in, while 16.67% （4/24） benign endometrium diseases showed earlier wash-in and 83.33 % （20/24） showed same or later wash-in. Meanwhile, 82.61% （19/23） endometrial carcinoma and 62.50~ （15/24） benign endometrial lesions showed earlier wash- out. There were significant difference between malignant group and benign group on either wash-in phases or wash-out phases （all P^0. 05）. The start time （AT） of benign and malignant lesions had no significant difference （P^0.05）, while the peak time （TTP） and peak intensity （PI） had significant difference （P〈0.05）. Conclusion CEUS phases and TIC pa- rameters of benign endometrial lesions and endometrial carcinoma have some different characteristics. Combining CEUS and TIC can provide weal＇thy information for differential diagnosis of benign and malignant endometrial diseases.

关 键 词：超声检查 子宫内膜肿瘤 时间-强度曲线 

分 类 号：R445.1[医药卫生—影像医学与核医学] R711.74[医药卫生—诊断学]