慢性阻塞性肺疾病与肺癌关系的研究进展  

Research Progress in Correlation between Chronic Obstructive Pulmonary Disease and Lung Cancer

作　　者：周心怡[1] 万毅新[1] 

机构地区：[1]兰州大学第二医院呼吸科,兰州730030

出　　处：《医学综述》2013年第7期1202-1204,共3页Medical Recapitulate

基　　金：甘肃省自然科学基金(1010RJZA097)

摘　　要：慢性阻塞性肺疾病(COPD)是临床的常见疾病,肺癌是最常见的恶性肿瘤之一,发病率和病死率均很高。近年来,国内外多项研究提示两者存在相关性,但机制尚未完全明确;推测两者具有共同的病理生理学基础,可能与烟雾暴露、慢性炎性反应、肺功能下降、遗传易患因素以及免疫调节异常有关。该文就COPD与肺癌的关系研究进展予以综述,为两者的早期预防、诊断提供帮助。Chronic obstructive pulmonary disease （COPD） is a clinically common disease, and lung cancer is one of the mzst common malignant tumors with high incidence and mortality. In recent years, a lot of studies in China and abroad indicate that the two are correlated while the mechanisms are not fully clear yet. It＇s speculated that the two may have common pathophysiological basis, and are probably realted with exposure to smoke, chronic inflammation, lung function decline, genetic suspetibility and immnnomodulation abnormality. Here is to make a review on the research progress of correlation between COPD and lung cancer, to provide help for early prevention and diagnosis of the two diseases.

关 键 词：慢性阻塞性肺疾病 肺癌 关联 

分 类 号：R563[医药卫生—呼吸系统]