微波辅助提取瑞香狼毒总黄酮工艺条件的优化  

Microwave assisted extraction of total flavonoids of stellera chamaejasme L.

作　　者：龚磊[1] 黄小容[1] 龚其海[2] 许洁[3] 颉江敏[4] 李玲如[5] 

机构地区：[1]遵义医学院附属医院药剂科,遵义563003 [2]遵义医学院药理学教研室,遵义563003 [3]遵义医学院预防医学教研室,遵义563003 [4]遵义医学院药学院,遵义563003 [5]遵义医学院药物制剂2008届毕业生,遵义563003

出　　处：《郑州大学学报（医学版）》2013年第2期242-245,共4页Journal of Zhengzhou University(Medical Sciences)

基　　金：教育部长江学者和创新团队发展计划项目IRT1197

摘　　要：目的:优化微波辅助提取瑞香狼毒总黄酮的工艺条件。方法:采用正交实验方法,考察料液比、溶剂乙醇浓度、微波功率、提取时间对总黄酮得率的影响,确定微波辅助提取瑞香狼毒总黄酮的最佳工艺条件。结果:微波辅助提取瑞香狼毒总黄酮的最佳条件为料液比1:25、乙醇体积分数90%、微波功率900W、提取时间60s,总黄酮平均得率为33.184mg/g。结论:微波辅助法提取瑞香狼毒总黄酮简单、易行,且快速、节能,值得推广应用。Aim： To investigate the optimal conditions of microwave-assisted extraction of total flavonoids from stellera chamaejasme L. . Methods： The orthogonal test method was employed to study the effects of the solvent concentration,sol-id to liquid ratio,microwave power,and irradiation time on the total flavonoid content,and determine the optimum condi-tions of microwave-assisted extraction stellera chamaejasme L. . Results： The optimal conditions for microwave-assisted ex-traction of total flavonoids from stellera chamaejasme L. was 90% solvent concentration,solid-liquid ratio of 1： 25,the mi-crowave power of 900 W,irradiation time of 60 s,and the total flavonoids average yield was 33. 184 mg / g. Conclusion： The microwave-assisted extraction method is simple,easy,and fast,energy-saving for the extraction of total flavonoids from stellera chamaejasme L. .

关 键 词：瑞香狼毒 总黄酮 微波辅助萃取 紫外-可见分光光度法 正交试验 

分 类 号：TQ460.6[化学工程—制药化工]