幼年斑马鱼的视觉系统与捕食行为  

Visual system and prey capture behavior of larval zebrafish

作　　者：李小泉[1] 杜久林[1] 

机构地区：[1]中国科学院上海生命科学研究院神经科学研究所,神经科学国家重点实验室,上海200031

出　　处：《遗传》2013年第4期468-476,共9页Hereditas（Beijing)

基　　金：国家重点基础研究发展计划(973计划)项目(编号:2011CBA00400);中国科学院战略性先导科技专项(编号:XDB02040300)资助

摘　　要：神经环路的研究是揭示动物行为神经机制的关键。斑马鱼作为一种低等脊椎动物,在神经环路的研究中有着独特优势。文章描述了斑马鱼视觉系统及其下游的神经环路,重点讨论了它们在捕食行为中的可能作用。斑马鱼捕食行为主要依赖于视觉功能,该过程涉及到视觉-运动通路各个层次的神经环路,包括下游的网状脊髓命令神经元、脊髓内部的运动控制环路以及一些亟待研究的功能单元。随着在体记录和操纵神经元活动技术的成熟,以及行为学范式的完善,对斑马鱼捕食行为相关神经环路的研究将在未来数年内迅速发展,同时也将推动神经科学相关研究的进步。Studying neural circuits is a crucial step for understanding neural mechanisms underlying animal behaviors. Larval zebrafish is a low vertebrate animal model with incomparable advantages in neural circuit study. In this review, we describe the zebrafish visual system and its downstream targets, with special emphasis on their possible roles in prey cap- ture behavior. Prey capture is executed mainly through the visual system and its downstream circuits, including reticulospi- nal commanding neurons, motor-controlling circuits within the spinal cord, and other un-identified functional units. With the development of approaches in monitoring and manipulating neuronal activity and behavioral assays, we will get deep insights about neural basis for prey capture in near future, which will shed light on elucidating neural circuit mechanisms of behavior.

关 键 词：斑马鱼 视觉系统 捕食行为 神经环路 

分 类 号：Q436[生物学—生理学]