血液病患者输血不良反应调查分析  

Investigation and analysis of adverse transfusion reactions of hemopathy patients

作　　者：于彦居[1] 孟宇[2] 曹建宇[1] 霍树辉[1] 

机构地区：[1]沧州市中心医院输血科,河北沧州061000 [2]吉林大学白求恩医学院

出　　处：《临床血液学杂志（输血与检验）》2013年第2期247-248,共2页Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)

摘　　要：目的:探讨血液病患者急性输血反应的发生率,分析原因,制定有效的预防措施。方法:收集2009-2011年血液内科发生的输血反应回报单,统计分析输血反应的情况。结果:14880人次受血者,210例发生输血反应,发生率1.41%。其中非溶血性发热性输血反应(FNHTR)106例,占0.72%;过敏性输血反应(ATR)101例,占0.68%;溶血性输血反应(HTR)3例,占0.02%;输注去白红细胞悬液、红细胞悬液、血浆和血小板占输血反应的发生率分别为1.01%、1.80%、1.39%和1.87%。结论:血液病患者输血反应发生率为1.41%,主要是FNHTE和ATR。输血前联合使用多种药物,输注去白红细胞成分和不规则抗体筛查可以有效降低血液病患者的输血不良反应发生率。Objective：To discuss the incidence of acute transfusion reaction of hemopathy patients,analyse the causes and make effective preventive measures. Method： Data of the transfusion reactions were collected from 2009 to 2011 ,to make statistic analysis of patients transfusion reactions,which were from the feedbacks of our hematology department. Result： Among 14 880 patients who received blood transfusions, transfusion reactions were ob- served in 210 cases,accounting for 1.41%. The majority of the 106 transfusion--related fatalities were due to febrile nonhemolytic transfusion reaction（FNHTR）, which accounts for 0. 72%;101 cases were caused by allergic transfusion reactions（ATR）, accounting for 0.68% the minority of the 3 post-transfusion fatalities were due to hemolytic transfusion reactions（HTR）, accounting for 0.02 %. Besides, the transfusion reaction incidences of leukocyte-depleted CRCs,CRCs, plasma and platelet account for 1.01%, 1.80%, 1. 39% and 1. 87%, respectively. Conclusion： The incidence of transfusion reactions of hemopathy patients account for 1.41%,which mainly include FNHTE and ATR. Combined application of medicine before blood transfusion, leukocyte--depleted CRCs and screening of irregular antibody could effectively decrease the adverse transfusion reaction incidence of the hemopathy patients.

关 键 词：血液病 输血 不良反应 

分 类 号：R55[医药卫生—血液循环系统疾病]