1例产酶大肠埃希杆菌的用药监护  

Pharmaceutical care on a patient with Escherichia coli (ESBL+)infection

作　　者：刘秀芹[1] 刘行梅[2] 王莉梅[3] 孙丽蕊[4] 

机构地区：[1]吉林省抚松县医院药剂科,134500 [2]吉林大学第二医院药品管理部 [3]一汽总医院(吉林大学第四医院)药学部 [4]吉林大学第一医院药剂科

出　　处：《中国实用医药》2013年第7期198-199,共2页China Practical Medicine

摘　　要：目的研究产酶大肠埃希杆菌感染的治疗方法和用药监护。方法对1例肺病感染患者进行病例跟踪,分析更换抗生素的原因,总结使用不同抗生素的使用效果。结果长期使用三代头孢,使产酶大肠埃希杆菌的耐药性增加,但对复合三代头孢仍较敏感。结论随着产酶大肠埃希杆菌耐药性的逐年递增,其抗生素的治疗应做药学监护。Objective The objective of the article is to study the treatment and pharmaceutical care of Escherichia coli （ESBL＋）infection. Methods By tracking a case of a patient with pulmonary infection, it was analysised the replacement of antibiotics, summarized the effect of different antibiotic. Results The long term use of three generation cephalosporins made the drug resistance of Escherichia coli （ESBL＋）increase. However, the three generation cephalosporin/Enzyme inhibitors were still sensitive to Escherichia coli （ESBL＋）. Conclusion Because the drug resistance of Escherichia coli （ESBL＋）increased year by year, the pharmaceutical care should be done in antibiotic treatment.

关 键 词：产酶大肠埃希杆菌 耐药性 药学监护 

分 类 号：R451[医药卫生—治疗学]