中国成年人体力活动与代谢综合征发病关系的前瞻性队列研究  被引量:13

Relationship between physical activity and the incidence of metabolic syndrome in Chinese adults:a prospective cohort study

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作  者:孟德敬[1] 陈纪春[1] 黄建凤[1] 李莹[1] 赵连成[1] 刘小清[2] 李建新[1] 曹杰[1] 俞玲[3] 邓颖[4] 陈娜萦[5] 郭东双 阮连生 顾东风[1] 

机构地区:[1]中国医学科学院北京协和医学院国家心血管病中心阜外心血管病医院循证医学部,北京100037 [2]广东省心血管病研究所流行病研究室 [3]福建省立医院心内科 [4]四川省疾病预防控制中心慢性非传染性疾病预防控制所 [5]广西壮族自治区疾病预防控制中心慢病科 [6]山西省盂县人民医院 [7]舟山市普陀区心脑血管病防治研究所

出  处:《中华预防医学杂志》2013年第4期312-317,共6页Chinese Journal of Preventive Medicine

基  金:围家“十一五”科技支撑计划(2006BA101A01)

摘  要:目的分析中国成年人体力活动水平与代谢综合征(Ms)发病的关系。方法在2007-2008年,对参加1998年中国心血管病流行病学多中心协作研究和2000-2001年中国心]血管健康多中心合作研究的35-74岁的成年人进行了随访。最终将资料完整并符合要求的11512名研究对象纳入本研究,其中男性5563名,女性5949名。捌查其人口学特征、体力活动、吸烟、饮酒情况,进行MS相关组分检测。依据平均每天体力活动总代鲥当量(metabolicequivalent,MET)值将总人群按照四分位数法分组;依据工作时体力活动强度将研究对象分为极轻、轻、中及重度广作强度组。采用二分类logistic模型进行体力活动与Ms发病关系分析。结果平均随访8.1年后,Ms发病2527例,年发病率为2.71%(2527/93178.68)。经多因素logistic回归分析后,与体力活动〈32.00MET·h·d^-1组[年发病率为3.19%(697/21830.74)]相比,32.00-37.85、37.86-52.29和/〉52.30MET·h·d^-1组[年发病率分别为2.82%(690/24504.25)、2.73%(661/24179.36)和2.11%(479/22664.33)]MS发病风险的RR(95%C/)值分别为1.05(0.92-1.19)、0.98(0.86-1.12)和0.68(0.59-0.80)(X^2赵势=34.23,P〈0.05)。同工作强度极轻组[年发病率为2.76%(402/14588.33)]相比,从事轻、中、重度体力活动工作者[年发病率分别为2.86%(648/22663.41)、2.40%(455/18956.14)和1.89%(344/18173.86)]发病风险RR(95%CI)值分别为0.80(0.69-0.92)、0.70(0.59-0.82)和0.54(0.45-0.65)(x2∞#=42.34,P〈0.05)。结论随着体力活动总量以及T作强度的增加,MS的发病风险逐渐降低。Objective To investigate the association between physical activity (PA) and the incidence of metabolic syndrome (MS) in Chinese adults. Methods Data on PA and other variables were obtained at the baseline examination of China Multi-center study of Cardiovascular Epidemiology in 1998 and of International Collaborative study of Cardiovascular Disease in Asia (InterASIA) during 2000 - 2001. Follow-up study was conducted in 2007 -2008. A total of 11 512 Chinese adults aged 35 -74 years (5563 men and 5949 women) were included in the final data analysis. Information on demographics, PA, smoking and alcohol consumption were obtained and components of MS were examined. Participants weredivided into four groups according to quartile of total metabolic equivalent (MET) values per day. In addition, subjects were grouped into the following categories aecording to occupational PA: inactive, light, moderate and vigorous. Binmy logistic model was used to examine the association between PA and the incidence of MS. Results A total of 2527 cases with MS were documented during an average following up of 8. 1 years. The annual incidence rate of MS was 2. 71% (2527/93 178.68). After multivariate logistic regression analysis, compared with participants with total PA volume 〈 32.0 MET·h·d^-1 ( annual incidence rate was 3. 19% (697/21 830. 74) ) ,the RR (95% CI) value of participants with total PA volume during 32. 00 -37.85,37.86 -52. 29,and ≥52. 30 MET ·h·d^-1 was 1.05(0. 92 - 1.19) ,0. 98(0. 86 - 1.12) , and 0. 68 (0. 59 0. 80) respectively ( 2 = 34. 23, P 〈 0. 05 ) with corresponding annual - , X^2trend, incidence rates of 2.82% (690/24 504. 25) ,2. 73% (661/24 179.36) and 2. 11% (479/22 664. 33). In addition, compared to inactive occupational PA ( annual incidence rate was 2. 76% (402/14 588.33 ) ), the corresponding RR (95%CI) value was 0. 80(0. 69 -0. 92) ,0. 70(0. 59 -0. 82) ,and 0. 54(0. 45 -0. 65) (X^2trend =42. 34,P 〈 0. 0

关 键 词:代谢综合征X 发病率 队列研究 体力活动 

分 类 号:R589[医药卫生—内分泌]

 

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