米索前列醇联合利多卡因局部应用于人工流产术中的临床研究  

作　　者：夏建丽[1] 刘娇兰 尹笑珍 曹自华 魏守红[1] 敖银柳 谢增霞[1] 

机构地区：[1]广东省东莞市长安医院,广东523843

出　　处：《当代医学》2013年第12期85-86,共2页Contemporary Medicine

摘　　要：目的探讨米索前列醇联合利多卡因局部应用于人工流产术中的使用安全性、镇痛效果、术中及术后可能发生的并发症。方法选择2010年1月～2012年6月期间600例早期妊娠需人工流产的病例作为研究对象。随机分为两组:治疗组300例,给予米索前列醇联合利多卡因局部应用;对照组300例,给予静脉推注酒石酸布托啡诺及丙泊酚静脉全麻。结果治疗组与对照组扩张宫颈效果分别为95.67%、86.00%,两组差异有显著性(P<0.05)。结论米索前列醇联合利多卡因局部应用优于静脉全麻,且安全性高,不良反应少,费用低,节省了较多的医疗资源,值得临床推广。Objective To explore the safety and the analgesia effect of misoprostol combined with lidocaine in artificial abortion, and the complications possible while and after the operation. Methods To choose 600 cases of women who need artificial abortion from January 2010 to June 2012 in department of gynaecology and obstetrics of our hospital and randomLy divide them into two groups, the treatment group and the control group, using two different treatments. Results The cervix-dilating effect of the two groups are 95.67% and 86.00% respectively, so there are significant differences between the two （P〈0.05）. Conclusion Partial use of misoprostol combined with lidocaine is superior to intravenous anesthesia and the former is safer with less side effects and lower cost, which can save more medical resources, so it is worthy of clinical promotion.

关 键 词：米索前列醇 利多卡因 局部应用 人工流产 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]