海乐普预防输卵管再通术后阻塞的疗效观察  

作　　者：邓军[1] 武兴杰[1] 黄树圭[1] 李军[1] 

机构地区：[1]广东药学院附属第一医院介入科,广东510080

出　　处：《当代医学》2013年第12期133-134,共2页Contemporary Medicine

摘　　要：目的研究海乐普(壳聚糖衍生物酰氨基葡萄糖)预防输卵管介入再通术后再阻塞的临床疗效。方法选取112例输卵管阻塞性患者,随机分为研究组(34例)和治疗组(78例)。研究组输卵管再通后行防阻塞液和海乐普灌注,治疗组再通后只单纯行防阻塞液灌注治疗。结果研究组阻塞输卵管再通率为96.8%(60/62),治疗组为97.4%(148/152);研究组术后12个月内妊娠率为35.3%(12/34),治疗组为16.7%(13/78),两组术后妊娠率比较,差异有统计学意义(P<0.05)。结论防阻塞液加海乐普比单用防阻塞液更能有效预防输卵管再通术后再阻塞,值得临床推广应用。Objective To investigate the efficacy of derivatives of glucose acyl chitosan to prevent tubal obstruction after recanalization surgery.Methods 112 patients with tubal obstruction were divided into two groups randomLy.The research group（n=34） was injected with injectionof prentvention restenosis and derivatives of glucose acyl chitosan,and the comparion group （n=78） with injection of prentvention restenosis only.Results The recanalization rates of two groups were 96.8%（60/62） and 97.4%（148/152）.The pregnancy rate in the research group was 35.3%（12/34）,and the comparion group was 16.7%（13/78） in the following 12 months after recanalization surgery.There is a significant difference between the two groups （P〈0.01）.Conclusion Comparied with injection of prentvention restenosis only, derivatives of glucose acyl chitosan and injection of prentvention restenosis are more effective to prevent the recurrence of tubal obstruction after interventional recanalization surgery.

关 键 词：海乐普 输卵管再通术 输卵管阻塞 

分 类 号：R711.6[医药卫生—妇产科学]