慢性疼痛患者注意偏向和焦虑的关系  

Relation between attention biases and anxiety in chronic pain patients

作　　者：陈国良[1,2] 单墨水[1,2] 路桂军[1] 高谦[1] 崔红[1] 

机构地区：[1]解放军总医院,北京100853 [2]沈阳军区大连疗养院215临床部,辽宁大连116041

出　　处：《解放军医学院学报》2013年第4期360-362,共3页Academic Journal of Chinese PLA Medical School

基　　金：国家科技支撑计划(2013BAI08B03)~~

摘　　要：目的探讨慢性疼痛患者对痛觉相关信息是否存在注意偏向。方法采用E-prime 2.0程序编写情绪Stroop范式,记录并比较慢性疼痛患者及健康对照组(各20例)对3类词汇(包括中性、痛觉、威胁)颜色命名的反应时及正确率,考察慢性疼痛患者的注意偏向。结果慢性疼痛患者对痛觉相关词汇的颜色命名反应时长于中性词汇[(786.02±18.15)ms vs(774.73±17.34)ms,P<0.05],威胁相关词汇反应时长于中性词汇[(792.35±17.72)ms vs(774.73±17.34)ms,P<0.05];健康对照组威胁相关词汇反应时长于中性词汇[(779.75±20.99)ms vs(764.74±20.53)ms,P<0.05],对痛觉相关词汇的颜色命名反应时与中性词汇无统计学差异。重复测量方差分析发现存在刺激类别的主效应(F=18.86,P<0.01),以及组别和刺激类别的交互效应(F=4.48,P<0.05)。慢性疼痛患者痛觉相关词汇注意偏向与疼痛持续时间无关,与患者焦虑水平显著相关(r=0.471,P<0.05)。结论慢性疼痛患者存在对痛觉相关信息的注意偏向,并且与焦虑水平有密切关系。Objective To study the attention biases to pain-related information in chronic pain patients.Methods Attention biases in 20 chronic pain patients and 20 healthy controls to pain-related words were recorded with E-prime 2.0 program,Stroop task.Results The reaction time（RT） to pain-related words and threaten words was longer than to neutral words in chronic pain patients（786.02±18.15 ms vs 774.73 ±17.34 ms,792.35±17.72 ms vs 774.73±17.34 ms,P 0.05）.The RT to threaten-related words was longer than to neutral words in healthy controls（779.75±20.99 ms vs 764.74±20.53 ms,P 0.05） whereas no significant difference was found in pain-related words and neutral words.Variance analysis showed a dominant effect of stimulation types（F=18.86,P 0.01） and an interactive effect between group types and stimulation types（F= 4.48,P 0.05）.Pain-related words were not related with pain-lasting time but with anxiety in chronic pain patients with attention biases（r=0.471,P0.05）.Conclusion Chronic pain patients suffer attention biases to pain-related information,which is significantly related to their anxiety.

关 键 词：慢性疼痛 注意偏向 情绪斯特鲁普 焦虑 对照研究 

分 类 号：R395.3[哲学宗教—心理学]