羟丙基-β-环糊精-多壁碳纳米管复合材料与扁桃酸的吸附作用  

Interaction of Hydroxypropyl-β-cyclodextrin Modified Multi-walled Carbon Nanotubes and Mandelic Acid

作　　者：李三清[1] 刘耀驰[2] 于金刚[2] 

机构地区：[1]解放军第425医院感染科,海南三亚572000 [2]中南大学化学化工学院有色金属资源化学教育部重点实验室,长沙410083

出　　处：《科技导报》2013年第11期60-64,共5页Science & Technology Review

基　　金：国家自然科学基金(No.21201181);教育部高等学校博士学科点专项科研基金(新教师类)(20110162120070);湖南省科技计划项目(2011FJ3175;2012rs4007);有色金属资源化学教育部重点实验室开放基金(No.2012-KF-04)

摘　　要：采用硝酸氧化法制备氧化多壁碳纳米管(MWNTs-COOH),在其表面引入羧基。以对甲苯磺酸(PTSA)为催化剂、二甲亚砜(DMSO)为溶剂,采用羟丙基-β-环糊精(HP-β-CD)修饰MWNTs-COOH,制备了分散性较好的羟丙基-β-环糊精-多壁碳纳米管(HP-β-CD-g-MWNTs)复合材料。经透射电镜(TEM)、傅里叶变换红外光谱(FT-IR)、热重分析(TGA)等测试后表明,HP-β-CD被成功接枝到多壁碳纳米管(MWNTs)表面。分散性研究结果表明,HP-β-CD-g-MWNTs复合材料在水溶液中的分散能力达到2.3mg/mL,这一属性使得该材料有望成为医学材料或药物载体材料。采用紫外-可见(UV-Vis)吸收光谱法研究扁桃酸与HP-β-CD-g-MWNTs复合材料的相互作用,结果表明扁桃酸可能通过π-π堆积、极性相互作用及氢键吸附在复合材料表面。基于上述分子间作用力的形成,与碳纳米管作用的分子可望实现从碳纳米管表面得到控制释放或缓释。Carboxyl groups are oxidized by nitric acid and introduced onto multi-walled carbon nanotubes （MWNTs）. Calalyzed by ptoluenesulfonic acid （PTSA）, the oxidized MWNTs （MWNTs-COOH） are reacted with hydroxypropyl-β-cyclodextrin （HP-β-CD） to obtain HP-β-CI）-g-MWNTs with good dispersivily. The prepared composites are fully characterized by Transmission Eleelrou Microscopy （TEM）. Fourier Transform infrared （FT-IR） spectroscopy, and thermogravimetrie analysis （TGA）, the results indicate thai HP-β-CD is sueeessfillly grafted onto MWNTs. The dispersion performance lest indicates that HP-β-CD-g-MWNTs are well-dispersed in the aqueous solutions, thus the composites are able to find their polenlial applications in bitmledical materials or drug deliveries. The interactions between HP-β-CD- g-MWNTs and mandelie acid are inw,stigated by using Uhraviolet-Visible light （UV-Vis） absorption spectrum. The rcsuhs indicate that mandelie acid is adsorbed on the surface of HP-β-CD-g-MWNTs by conjunet interactions, snch as π-π stacking, polar interaction, anti hydrogen bonding. Due to the molecular interactions, the absorbed molecules are able to realize controlled-releasing or sustained- sustasing from the surtace of MWNTs.

关 键 词：多壁碳纳米管 羟丙基-Β-环糊精 分散性 扁桃酸 紫外-可见吸收光谱 

分 类 号：TB383.1[一般工业技术—材料科学与工程]