早期应用无创正压通气救治重症支气管哮喘的临床效果  

Clinical Effect of Early Use of Noninvasive Positive Pressure Ventilation in the Treatment of Severe Bronchial Asthma

作　　者：罗裕锋[1] 杨思敏[1] 杨日焰[1] 

机构地区：[1]惠州市中心人民医院重症医学科,广东惠州516001

出　　处：《中国医药指南》2013年第4期402-402,404,共2页Guide of China Medicine

摘　　要：目的探讨早期应用无创正压通气救治重症支气管哮喘的临床效果。方法选取2009年12热活血汤进行治疗。结果研究组患者在行无创正压通气4h后HR、R和PaCO2、均比治疗前治疗前有明显降低,而pH值和PaO2均比治疗前有明显升高,差异具有统计学意义(P<0.05)。研究组患者经鼻导管吸氧24h候,上述各项指标才有明显改善(P<0.05)。同时,分别于4、24h比较两组患者的HR、RR和PaCO2、pH值和PaO2,研究组的改善程度均明显优于对照组,差异具有统计学意义(P<0.05)。研究组36例患者均未出现与呼吸机相关的严重并发症。结论早期应用无创正压通气救治重症支气管哮喘,可在一定程度上可以降低心率和呼吸频率,缓解呼吸困难,是救治急性重症哮喘的有效方法。Objective To investigate the early use of noninvasive positive pressure ventilation in the treatment of severe bronchial asthma clinical effect. Methods From 2009 12 heat and Activating Blood Decoction treatment. Results The study group underwent noninvasive positive pressure ventilation for 4 hours after HR, R and PaCO2, than that before treatment before treatment were decreased significantly, while pH and PaO2 were significantly increased than before treatment, the difference was statistically significant （P〈0.05）. Research group of patients with nasal catheter oxygen inhalation for 24 hours, the indicators have improved significantly （P〈0.05）. At the same time, in 4, 24 hours compared with two groups of patients with HR, RR and PaCO2, pH and PaO2, study group of the degree of improvement was significantly better than the control group, the difference was statistically significant （P〈0.05）. The study group of 36 patients without severe complication associated with ventilator. Conclusion The early use of noninvasive positive pressure ventilation in the treatment of severe bronchial asthma, and to some extent can reduce heart rate and respiration, relieving dyspnea, is the treatment of acute severe asthma effective method.

关 键 词：早期 无创正压通气 重症支气管哮喘 

分 类 号：R562.25[医药卫生—呼吸系统]