DEXA、QUS在绝经后骨质疏松脊柱骨折诊断中的应用与探讨  

Usefulness of DEXA and QUS measurement in predicting vertebral fracture in osteoporotic patients

作　　者：林华[1] 包丽华[2] 韩祖斌[1] 田成功[1] 孙燕芳[1] 魏海燕[1] 

机构地区：[1]南京大学医学院附属鼓楼医院代谢性骨病防治研究中心,南京210008 [2]江苏省人民医院核医学科

出　　处：《中国骨质疏松杂志》2000年第2期13-15,共3页Chinese Journal of Osteoporosis

基　　金：南京市重点医学科技发展基金!ZKG9913

摘　　要：目的　探讨对比绝经后骨质疏松患者 DEXA与 QUS测量对骨质疏松脊椎骨折的预测能力。方法 :应用双能 X线骨密度仪 (DEXA,L unar,DPX- IQ)和超声骨强度仪 (QUS,Sunlight Om-nisense,Research)对 4 9例绝经后骨质疏松脊柱骨折患者脊柱、股骨近端和桡骨、胫骨进行测定、比较。结果　 4 9例患者 DEXA腰椎 BMD- T值为 - 2 .99± 1.4 3,股骨近端 BMD- T值为 - 1.95± 1.14;而QUS桡骨 SOS- T值为 - 3.12± 0 .79,胫骨 SOS- T值为 - 1.6 7± 1.73。比较发现 :腰椎 BMD对脊柱骨质疏松骨折有较好的提示 ,而超声的桡骨 SOS对脊柱骨质疏松骨折也有敏感的预示能力。结论　骨质疏松不仅有骨量的减少 ,还包括骨结构的破坏 ,严格的骨质疏松诊断及其骨折预测 ,应提倡多部位DEXA和 QUS测定的联合判断。Objective To study the usefulness of DEXA and QUS measurement in predicting vertebral fracture in postmenopausal osteoporotic patients. Methods Bone mineral density was measured in 49 postmenopausal osteoporotic patients by DEXA(DPX IQ,Lunar) and QUS (Research,Sunlight Omnisense). DEXA measurement was performed at the spine and the proximal femur,and QUS measurement was performed at the distal radius and the tibia. Results DEXA(BMD,T\|score):Spine -2.99±1.43; femur -1.95±1.14. QUS (SOS,T\|score):radius -3.12±0.79;tibia -1.67±1.73. It is indicated that the BMD of spine and the SOS of radius are good indices for predicting vertebral fracture in postmenopausal osteoporotic patients. Conclusion Osteopososis involves not only low bone mass,but also bone microarchitectural deterioration of bone tissue. The diagnosis of osteoporosis and the prediction of osteoporotic fracture should be based on multi\|site measurements of DEXA and QUS.

关 键 词：骨质疏松骨折 骨密度 骨结果 DEXA QUS 诊断 

分 类 号：R681.04[医药卫生—骨科学] R683.204[医药卫生—外科学]