最小重要差值及其在中医临床研究中的应用展望  

The Prospective of Minimal Important Difference and Its Application in Clinical Researches of Chinese Medicine

作　　者：路桃影 吴大嵘 

机构地区：[1]广州中医药大学第二附属医院(广东省中医院)临床疗效项目办公室,广州510120

出　　处：《中国中西医结合杂志》2013年第4期544-548,558,共6页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家重点基础研究发展计划(973计划)(No.2011CB505404);国家中医药管理局公益性行业科研专项(No.200707004);广东省财政厅项目"中医药疗效评价体系理论模型的论证与研究"(No.粤财Ⅰ[2006]143)

摘　　要：最小重要差值(minimal important difference,MID)是近年来提出的一个有关疗效评价的概念,MID具有一定的特点和临床研究意义。MID的方法包括锚定法、分布法、专家意见法和文献分析法等,不同方法有各自的优缺点,在确定MID时,最好能根据研究目的综合使用。本文阐述了MID在中医临床研究领域应用的意义、范围和评估方法,认为MID相关的研究与应用仍亟需加强。Minimal important difference （MID） is a concept in regards of efficacy evaluation in recent years. MID has its features and clinical significance. MID methods include anchor-based methods, distribution-based methods, expert consensus methods, literature analysis methods, and so on. All these methods have their own advantages and disadvantages. In confirming MID, you′d better use them comprehensively according to the research objectives. The significance, range, and evaluation methods of MID in the clinical research of Chinese medicine were clarified. It is necessary to strengthen MID correlated researches and applications.

关 键 词：最小重要差值 疗效评价 中医临床研究 锚定法 分布法 

分 类 号：R24[医药卫生—中医临床基础]