Applications of polymer single nanochannels in biosensors  

作　　者：HOU GuangLei PENG ZhiJian TIAN Ye ZHANG HuaCheng JIANG Lei 

机构地区：[1]School of Engineering and Technology,China University of Geosciences [2]Beijing National Laboratory for Molecular Sciences (BNLMS),Institute of Chemistry,Chinese Academy of Sciences

出　　处：《Chinese Science Bulletin》2013年第13期1473-1482,共10页

基　　金：supported by the National Basic Research Program of China (2011CB935700);National Natural Science Foundation of China(21201170, 11290163, 21121001, 91127025, 21171171);Key Research Program of the Chinese Academy of Sciences (KJZD-EW-M01);Beijing National Laboratory for Molecular Sciences (CMS-PY-201243)

摘　　要：There are many elaborate masterpieces exist in natural world. Learning from nature, people developed serial intelligent biomimetic devices. Biomimetic smart nanochannels received widespread attention for mimicking biological processes in bodies. Excellent stability, tailorable surface characteristics and nano-size effects rend polymer single nanochannel an ideal candidate for constructing sensitive and reproducible biosensors. Nanochannels are responsive for special analytes while appropriate recognition elements are modified in channels wall. In this review, we summarized recent works in contructing biosensors that are using polymer single nanochannels for detecting various analytes.There are many elaborate masterpieces exist in natural world. Learning from nature, people developed serial intelligent biomi- tactic devices. Biomimetic smart nanochannels received widespread attention for mimicking biological processes in bodies. Ex- cellent stability, tailorable surface characteristics and nano-size effects rend polymer single nanochannel an ideal candidate for constructing sensitive and reproducible biosensors. Nanochannels are responsive for special analytes while appropriate recogni- tion elements are modified in channels wall. In this review, we summarized recent works in contructing biosensors that are using polymer single nanochannels for detecting various analytes.

关 键 词：生物传感器 纳米通道 聚合物 应用 纳米尺寸效应 仿生智能 生物过程 表面特性 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] TK124[自动化与计算机技术—控制科学与工程]