季鏻和金属对高张力六元环的双重稳定化作用  

Double Stabilization of Highly Strained Six-Membered Rings by Phosphonium and Transition Metal

作　　者：朱从青[1] 曹晓宇[1] 夏海平[1] 

机构地区：[1]厦门大学化学化工学院,厦门361005

出　　处：《有机化学》2013年第4期657-657,658-662,共6页Chinese Journal of Organic Chemistry

基　　金：国家重点基础研究发展计划(No.2012CB821600);国家自然科学基金(Nos.21174115;20925208);长江学者和创新团队发展计划资助项目~~

摘　　要：环炔和环内累积多烯作为有机合成的重要中间体,在合成化学中扮演着重要的角色.但是,对这类高活性物种的稳定化一直是学术界研究的热点和难点.近年,我们课题组发现季鏻和过渡金属具有双重稳定化作用,可以极好地稳定这类高张力环状化合物.对我们课题组在这方面的最新进展进行了综述.Cycloalkynes and cyclocumulenes have attracted considerable attention because they are key intermediates in or- ganic synthesis. Stabilization of these highly active species remains a challenge for synthetic chemists. Recently, we found that phosphonium and transition metal replacement can double stabilize these species. Using this strategy, a series of highly strained six-membered rings with remarkable stability have been synthesized. Herein, the latest progress of our group is re- viewed.

关 键 词：芳炔 金属杂环 季鏻 稳定化 张力环 

分 类 号：O626[理学—有机化学]