钯催化的有机硼化物与羧酸衍生物的交叉偶联反应  

Palladium-Catalyzed Cross-Coupling Reaction of Organoboron Compounds with Carboxylic Derivatives

作　　者：杨军[1] 邓敏智[1] 于涛[1] 

机构地区：[1]中国科学院上海有机化学研究所,上海200032

出　　处：《有机化学》2013年第4期693-703,共11页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.20802088;91017006;90917017)资助项目~~

摘　　要：钯催化的交叉偶联反应是构建C—C键的常用方法,近年来,钯催化的有机硼化物与羧酸衍生物的交叉偶联反应已成为偶联反应研究中的热点.本文综述了最近十几年多种有机硼化物与酰氯、酸酐、羧酸、氯甲酸衍生物、羧酸活性酯、羧酸硫酯的交叉偶联反应研究进展,并对该反应在有机合成中的应用进行了讨论.Palladium-catalyzed cross-coupling reaction has emerged as an important strategy to the formation of C--C bond. Recently, palladium-catalyzed cross-coupling reaction between organoboron compounds and carboxylic derivatives has be- come a hotspot of organic chemistry. In this paper, recent researches of organoboron compounds with acyl chlorides, acid anhydrides, carboxylic acids, chloroformic derivatives, carboxylic esters and thiol esters in Suzuki cross-coupling are summa- rized, and the examples of these reactions in synthesis are also discussed.

关 键 词：羧酸衍生物 交叉偶联 钯催化剂 

分 类 号：O643.32[理学—物理化学]