血清降钙素原和C-反应蛋白在评价老年肺炎病情严重程度及预后中的价值探讨  

Value of serum procalcitonin and c-reactive protein for elderly pneumonia severity and prognosis

作　　者：阿丽娅.艾依提 白婷迪娜[2] 

机构地区：[1]新疆维吾尔自治区人民医院干四科,新疆乌鲁木齐830001 [2]新疆维吾尔自治区人民医院神经内科,新疆乌鲁木齐830001

出　　处：《中国医药导报》2013年第11期38-39,共2页China Medical Herald

摘　　要：目的探讨血清降钙素原和C-反应蛋白在老年肺炎病情严重程度及预后的临床价值。方法收集2010年5月-2012年5月在新疆维吾尔自治区人民医院接受治疗的社区获得性老年肺炎患者60例,按其严重程度分为A、B、C、三组。同时随机选取同一时期在新疆维吾尔自治区人民医院体检健康者20例作为对照组。比较各组患者血清血清降钙素原和C-反应蛋白水平的变化。结果 A、B、C组患者血清降钙素原水平和血清C-反应蛋白水平明显高于正常组,且C组血清降钙素原、C-反应蛋白水平均高于A、B组,比较差异均具有统计学意义(P<0.05)。结论肺炎病情越重的患者,其血清降钙素原和C-反应蛋白浓度越高,检测血清降钙素原、C-反应蛋白可有助于临床判断肺炎的严重程度。Objective To explore the value of serum procalcitonin and c-reactive protein for elderly pneumonia severity and prognosis. Methods 60 patients with community-acquired pneumonia treated in respiratory department clinics and wards were collected in our hospital from May 2010 to May 2012. Its severity divided into three group. 20 healthy eases were randomly selected from the same period in our hospital, as the control group. To compare serum procaleitonin and c-reactive protein of each groups. Results The serum proealcitonin and C-reactive protein of Group A, Group B, Group C was significantly higher than the control group and the group C serum procalcitonin and C-reactive protein levels was higher than group A, group B, the difference was statistically significant （P 〈 0.05）. Conclusion Patients with pneumonia more severe the disease, the higher the concentration of serum proealcitonin and C-reactive protein. Detection of serum procaleitonin and c-reactiye protein can contribute to the clinical judgment of severity of pneumonia.

关 键 词：血清降钙素原 C-反应蛋白 老年肺炎 病情预后 

分 类 号：R563.1[医药卫生—呼吸系统]