棘球绦虫感染犬粪抗原检测研究新进展  

Recent advances on development of coproantigen detection system for dogs infected with Echinococcus spp.

作　　者：张瑞妮[1,2] 吾拉木.马木提 

机构地区：[1]新疆医科大学基础医学院寄生虫教研室,乌鲁木齐830011 [2]新疆医科大学第一附属医院包虫病重点实验室,乌鲁木齐830054

出　　处：《中国人兽共患病学报》2013年第4期398-402,共5页Chinese Journal of Zoonoses

基　　金：国家自然科学基金项目(包虫感染犬免疫学和分子生物学鉴别诊断试剂盒的研究No.81160202)资助~~

摘　　要：棘球绦虫(Echinococcus spp.)感染的犬目前是人畜棘球蚴病主要传染源,因此对感染犬的动态监测、合理驱虫治疗是预防和彻底消灭包虫病流行的关键性措施之一。近年来,为了克服槟榔碱导泻法鉴定虫种和虫卵以及检测血清特异性循环抗原及抗体等方法的不足,各实验室开始应用ELISA双抗夹心法,试图建立棘球绦虫感染犬粪抗原的快速检测系统。本文对犬感染棘球绦虫的特异性粪抗原检测技术的最新进展作一综述。Currently, dogs infected with Echinococcus spp. are the main contagium of hydatid disease. Therefore, the conducting of dynamic monitoring and reasonable deworming of the dogs infected with Echinococcus spp. is one of the key measures for prevention and elimination of hydatid disease in epidemic areas. In recent years, in order to overcome the disad- vantages of identifying the parasite or eggs in dog feces by arecoline purgation and serum specific circulating antigens or anti bodies detection methods, scientists intend to establish a fast coproantigen detection system for diagnosis of dogs infected with Echinococcus spp. by using sandwich-ELISA method. This article reviews most recent advances on establishment of specific coproantigen detection techniques for dogs infected with Echinococcus spp.

关 键 词：棘球绦虫 ELISA双抗夹心法 抗体 EgAgB8 3重组蛋白 

分 类 号：R383.3[医药卫生—医学寄生虫学]