老年重症肺炎血清降钙素原水平与APACHEⅡ评分的相关性  

Correlation between levels of serum procalcitonin and APACHE Ⅱ in elderly patients with severe pneumonia

作　　者：徐志锋[1] 高永祺[1] 余梅娟[1] 陈发球[1] 徐文娟[1] 薛更寅[1] 

机构地区：[1]广东省江门市中心医院急诊科,广东江门529000

出　　处：《右江民族医学院学报》2013年第2期133-135,共3页Journal of Youjiang Medical University for Nationalities

摘　　要：目的探讨老年重症肺炎患者血清降钙素原水平(Procalcitonin,PCT)与急性生理和慢性健康状况(acute physiology and chronic health evaluation,APACHEⅡ)评分的相关性及两者结合对老年重症肺炎病情发展和预后的判断意义。方法选取75例老年重症肺炎患者,在治疗前均测定血常规、红细胞沉降率(erythrocyte sedimentation rate,ESR)、PCT水平,同时行APACHEⅡ评分。根据首次APACHEⅡ评分分组,≥20分的33例为高分组;<20分的42例为低分组。追踪14天,存活的52例为存活组,死亡组有23例。采用t检验、Pearson相关分析等统计方法,分析PCT与APACHEⅡ评分的相关性。结果高分组与低分组相比,血清PCT水平及APACHEⅡ分值差异有显著性(P<0.01或P<0.05),死亡组的PCT(3.36±2.76)ng/ml与APACHEⅡ分值(28.05±4.55)分与存活组相比差异有高度显著性(P<0.01)。PCT水平与APACHEⅡ评分呈正相关(r=0.414,P<0.01)。结论 PCT水平与APACHEⅡ评分有相关性,二者结合综合分析,对判断老年重症肺炎患者的病情和预后有重要的临床意义。Objective To explore the correlation between levels of serum procalcitonin （PCT） and acutephysiology and chronic health evaluation （APACHE Ⅱ ） score, and to study their value in combined judging disease development and predicting prognosis in elderly patients with severe pneumonia. Methods patients with severe pneumonia were selected and all were evaluated with APACHE Ⅱ score. The 75 elderly blood cell count, erythrocyte sedimentation rate （ESR）, PCT level were detected before treatment. All these patients were divided into high score group （33 cases, ≥20） and low score group （42 cases,〈20） based on initial A- PACHE Ⅱ score. After i4 days, the patients were divided into survival group （52 cases） and death group （23 cases）. The correlation between PCT and APACHE Ⅱ score was analyzed by statistical methods including t-- test and Pearson correlation analysis. Results PCT level and APACHE Ⅱ score were statistically different between high score group and low score group （ P〈0.01 or P 〈0.05）. PCT level [（3. 36±2.76） ng/ml] and APACHEⅡ score （28.05±4.55） in death group were statistically significant different from those in survival group （ P 〈0.01）. PCT level had positive correlation with APACHE Ⅱ score （ r =0. 414, P 〈0.01）. Con- elusion There was a positive correlation between PCT level and APACHEⅡscore, and they were very im- portant in evaluating the development and predicting disease in elderly patients with severe pneumonia.

关 键 词：老年人 肺炎 降钙素原 APACHE Ⅱ评分 

分 类 号：R563.1[医药卫生—呼吸系统]