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机构地区:[1]内蒙古医科大学研究生学院,呼和浩特010050 [2]内蒙古医科大学第一附属医院超声科 [3]内蒙古医科大学第一附属医院神经内科
出 处:《疑难病杂志》2013年第5期354-356,共3页Chinese Journal of Difficult and Complicated Cases
基 金:国家自然科学基金资助项目(No.81060120)
摘 要:目的应用血管回声跟踪技术评价2型糖尿病患者足背动脉早期硬化情况。方法 2型糖尿病患者40例(糖尿病组)和健康体检者40例(健康对照组),应用血管回声跟踪技术检测其足背动脉血管弹性指标:僵硬度(β)、压力应变弹性系数(Ep)、顺应性(AC)、脉搏波传导速度(PWVβ),比较2组足背动脉血管弹性改变。结果与健康对照组比较,糖尿病组足背动脉β、Ep、PWVβ均增高,分别为14.55±4.90和11.18±4.24、(199.08±69.68)kPa和(139.18±53.32)kPa、(8.49±1.58)m/s和(7.12±1.36)m/s,差异均有统计学意义(P<0.05);而AC值降低,分别为(0.08±0.05)mm^2/kPa和(0.10±0.04)mm^2/kPa,差异有统计学意义(P<0.05)。结论血管回声跟踪技术能够快速、无创地评价2型糖尿病患者足背动脉早期硬化。Objective To apply echo tracking technique in the evaluation of early dorsalis pedis artery sclerosis in patients with type 2 diabetes mellitus (DM). Methods Forty healthy subjects ( healthy control group) and forty type 2 DM patients( DM group) were enrolled in this study. All objects of study had been checked by conventional high frequency ultrasound to rule out intima media thickening and the formation of plaque, and the echo tracking technique was used to test arterial elasticity parameters, including arterial stiffness (13), pressure strain elastic modulus (Ep), arterial compliance (AC) and pulse wave conducting velocity (PWVI3), the vascular elasticity of dorsalis pedis artery were observed. Results Compared with the healthy control group, the β, Ep and PWVβ were higher significantly in the DM group ( P 〈 0.05 ) which were 14.55 ±4.90 vs 11.18 ±4.24,(199.08 ±69.68) kPa vs(139.18 ±53.32) kPa, (8.49 ±1.58) m/s vs(7.12 ±1.36) m/s respectively, AC was significantly lower in the DM group ( P 〈 0.05 ) , which were (0.08 ±0.05 )mmZ/kPa and (0.10 ±0.04) mm2/kPa respectively. Conclusion Echo tracking imaging technology is a convenient and non-invasive method which can be used to evaluate early dorsalis pedis artery atherosclerosis in patients with type 2 diabetes mellitus.
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