六种抗菌方案治疗沙眼衣原体性非淋菌性尿道炎的疗效分析  

The efficacy analysis of six antibacterial treatments of nongonococcal urethritis of chlamydia trachomatis

作　　者：朱永蒙[1] 黄凯 沈瑞芳[3] 

机构地区：[1]内蒙古医科大学第三附属医院综合办公室,内蒙古包头014010 [2]内蒙古包头市包钢集团预保中心,内蒙古包头014010 [3]内蒙古医科大学第三附属医院友谊分院,内蒙古包头014010

出　　处：《中国现代医学杂志》2013年第6期55-57,共3页China Journal of Modern Medicine

摘　　要：目的评价本地区目前常用的抗菌治疗方案对男性泌尿生殖道沙眼衣原体（Ct）感染的疗效。方法总结2009年1月~2011年12月在我院诊断为Ct感染的男性非淋菌性尿道炎（NGU）患者的抗生素使用情况并对其结果进行分析。结果不同治疗方案对Ct感染的NGU的总体治愈率为61.17%,疗效一般。不同的治疗方案对ct的清除差异无显著性（χ2=8.076,P〉0.05）。以阿奇霉素5 d口服治疗方案的疗效最佳,治愈率为77.14%,其次为米诺环素67.74%及克拉霉素66.67%治疗方案;而阿奇霉素1 g单剂口服治愈率仅为52.50%,左氧氟沙星及多西环素的治愈率也分别仅有52.17%及51.43%,疗效均较差。结论阿奇霉素5 d疗法对Ct的清除率较高,其次为米诺环素及克拉霉素;而阿奇霉素单剂疗法、左氧氟沙星、多西环素口服疗法效果较差,值得本地区临床医生关注。【Objective】To evaluate the antibacterial treatment programs for male patients of urogenital chlamydia trachomatis（Ct） infection.【Methods】To summarize the antibiotic use and the results of the Ct infected male patients of non-gonococcal urethritis（NGU） in our hospital from January of 2009 to December of 2011.【Results】A not very effective result of different treatments to Ct infection of NGU was achieved with an overall cure rate of 61.17%.And different treatments for removal of Ct were not statistically significant（χ2=8.076,P 0.05）.Among the treatments,the best one is orally taken azithromycin for 5 days with a cure rate of 77.14%,followed by minocycline and clarithromycin with the cure rate of 67.74% and 66.67% respectively.While the treatment of azithromycin 1 g single orally taken dose only yielded a cure rate of 52.50%,and the cure rate of levofloxacin and doxycycline treatment were only 52.17% and 51.43% respectively.【Conclusion】The Ct clearance by 5-days azithromycin treatment was higher,followed by minocycline and clarithromycin,while single-dose azithromycin,evofloxacin and doxycycline oral therapy is less effective.This result is worth an attention from the regional clinical doctors.

关 键 词：抗菌方案 沙眼衣原体 非淋菌性尿道炎 

分 类 号：R453.2[医药卫生—治疗学]