连翘酯苷对LPS诱导的肉鸡法氏囊中NO及抗氧化酶活性的影响  

Effect of Forsythiaside on NO and Antioxidant Enzyme Activity Induced by LPS in Bursa of Fabricius of Broiler Chickens

作　　者：赵玉莲[1] 陈俭清[1] 程广东[1,2] 吴悦[1] 李鹤[1] 李贤贤[1] 韩强[1] 李艳华[1] 

机构地区：[1]东北农业大学动物医学学院,黑龙江哈尔滨150030 [2]佳木斯大学生命科学学院,黑龙江佳木斯154007

出　　处：《中国家禽》2013年第8期17-19,共3页China Poultry

基　　金：国家科技支撑项目(2011BAD34B01-03);黑龙江省卫生厅课题(2012-267)

摘　　要：本试验研究了连翘酯苷对内毒素(LPS)诱导的肉鸡法氏囊中一氧化氮(NO)、总抗氧化能力(T-AOC)、总超氧化物歧化酶(T-SOD)、还原型谷胱甘肽(GSH)和丙二醛(MDA)含量的影响。结果表明:连翘酯苷组中T-AOC、T-SOD和GSH活性明显升高,与正常组比较差异显著(P<0.05);LPS组中NO和MDA含量明显升高,T-AOC、T-SOD和GSH活性明显降低,与正常组比较差异显著(P<0.05);连翘酯苷治疗组中NO和MDA含量明显降低,T-AOC、T-SOD和GSH活性明显升高,与LPS组比较差异显著(P<0.05)。研究结果表明:连翘酯苷可提高肉仔鸡抗氧化功能,并且可以抑制由LPS引起的氧化反应。This experiment was conducted to study the effect of forsythiaside on nitric oxide （NO）,total antioxidative capacity （T-AOC）, total superoxide dismutase （T-SOD）, gluta thione peroxidase （GSH） and malondialdehyde （MDA） in the bursa of Fabricius of broiler chicken induced by lipopolysaccharide （LPS）. The results showed that the activity of T-AOC, T-SOD and GSH in forsythiaside group were significantly elevated compared with normal control group （P〈0.05）. The contents of NO and MDA in LPS group were significantly elevated,and T-AOC,T-SOD and GSH activity was significantly reduced compared with normal control group （P〈0.05）. The contents of NO and MDA in forsythiaside treatment group were significantly reduced and T-AOC, T-SOD and GSH activity was significantly elevated compared with LPS group （P〈0.05）. The results indicated that forsythiaside could significantly improve antioxidant status and inhibit oxidation reaction caused by LPS.

关 键 词：连翘酯苷 肉鸡 法氏囊 一氧化氮(NO) 抗氧化酶活性 

分 类 号：S565.4[农业科学—作物学]