515例药源性血尿不良反应分析  

Analysis of 515 ADR Cases of Drug-induced Hematuria

作　　者：海丽萍 杨雪[2] 张惠霞[2] 

机构地区：[1]河南省省直第一医院,郑州450003 [2]河南省食品药品评价中心,郑州450004

出　　处：《中国药房》2013年第18期1696-1698,共3页China Pharmacy

摘　　要：目的:通过对药源性血尿的不良反应报告分析,探讨药品引起血尿的特点及一般规律。方法:收集2004-2012年河南省药品不良反应数据库中引起血尿的不良反应病例报告,采用回顾性研究的方法,对影响药源性血尿的因素进行统计和分析。结果:药源性血尿患者以60岁以上的老年患者发生几率最大,为19.42%;引起血尿的药品以抗微生物药、解热镇痛抗炎药为主,分别为总数的51.26%、18.45%。结论:安全、合理地使用药品,研究和避免血尿的诱发因素,对减少不良反应的发生有重要的临床意义。OBJECTIVE:To analyze ADR reports of drug-induced hematuria,and to investigate the characteristics and regularity of hematuria induced by drugs. METHODS:ADR reports of hematuria were collected from Henan ADR database during 20042012,and the influential factors of drug-induced hematuria were analyzed statistically in retrospective study. RESULTS:Drug-induced hematuria patients aged more than 60 years old mostly suffered from the disease,accoundting for 19.42%. The drugs inducing hematuria were mainly antimicrobial drugs,antipyretic and analgesic drugs,accounting for 51.26% and 18.45%. CONCLUSIONS:It is of great clinical significance to reduce the occurrence of ADR by safe and rational drug use and related factors study and avoidance of hematuria.

关 键 词：药源性血尿 不良反应 分析 

分 类 号：R969.3[医药卫生—药理学]