左氧氟沙星联合盐酸特拉唑嗪治疗慢性非细菌性前列腺炎68例疗效观察  

Therapeutic effects of levofloxacin combined with terazosin hydrochloride for treating 68 patients with chronic nonbacterial prostatitis

作　　者：翁感 

机构地区：[1]上海市徐汇区大华医院药械科,上海200031

出　　处：《实用临床医药杂志》2013年第7期141-143,共3页Journal of Clinical Medicine in Practice

基　　金：中国高校医学期刊临床专项资金(11320057)

摘　　要：目的探讨左氧氟沙星联合盐酸特拉唑嗪在治疗慢性非细菌性前列腺炎中的疗效。方法对本院2008年6月—2010年4月期间收治的68例慢性非细菌性前列腺炎患者采用左氧氟沙星联合盐酸特拉唑嗪进行治疗。观察治疗前后临床疗效、NIH-CPSI评分、尿流率变化及不良反应发生情况。结果 68例慢性非细菌性前列腺炎患者完成治疗后,显效44例(64.7%),有效18(26.5%)例,无效6例(8.8%),总有效率为91.2%。治疗后NIB-CPSI表评分较治疗前明显降低;最大尿流率及平均尿流率较治疗前明显升高。在治疗期间1例患者出现头晕、头疼,3例患者出现轻度腹泻。结论左氧氟沙星联合盐酸特拉唑嗪治疗慢性非细菌性前列腺炎疗效显著,无明显不良反应,值得临床推广使用。Objective To investigate the therapeutic effects of levofloxacin combined with terazosin hydrochloride in the treatment of chronic nonbacterial prostatitis （CNBP）. Methods Six- ty-eight patients with CNBP received in our hospital from June, 2008 to April, 2010 were treated with levofloxacin combined with terazosin hydrochloride. The clinical effects, NIH-CPSI score, changes of urine flow rate and conditions of adverse reactions were observed before and after treat- ment. Results After treatment, 44 cases were markedly effective （64.7%）, 18 cases effective （26.5%）, 6 cases non-effective and the total effectiveness rate was 91.2%. Compared with treat- ment before, NIB-CPSI score after treatment notably decreased, and the largest and mean urine flow rates also significantly increased. During treatment, 1 patient suffered from dizziness and headache, 3 patients from mild diarrhea. Conclusion In the treatment of CNBP, levofloxacin combined with terazosin hydrochloride, without conspicuous adverse reactions, has significant ther- apeutic effects, which is worthy of clinical popularization and application.

关 键 词：左氧氟沙星 盐酸特拉唑嗪 慢性非细菌性前列腺炎 

分 类 号：R697[医药卫生—泌尿科学]