临床核医学诊断所致患者内照射剂量估算软件的开发  

A New Software Developed for Internal Dose Assessments of Patients Undergone Diagnostic Nuclear Medicine Procedures

作　　者：易艳玲[1] 赵超[1] 杨莉 卓维海[1] 

机构地区：[1]复旦大学放射医学研究所,上海200032 [2]上海市辐射环境监督站,上海200065

出　　处：《中国辐射卫生》2013年第2期132-134,共3页Chinese Journal of Radiological Health

基　　金：上海市公共卫生优秀学科带头人培养计划支持(GWDTR201206)

摘　　要：目的配合ICRP推荐的最新组织权重因子,开发便于估算临床核医学诊断所致受检者与患者内照射器官剂量与有效剂量的软件。方法汇总国际放射防护委员会(ICRP)推荐的相关剂量转换系数并建立数据库,采用体积元S值法和ICRP推荐的最新组织权重因子分别计算器官剂量和有效剂量,利用C++计算机编程语言编写软件。结果该软件可估算临床核医学诊断应用中47种放射性核素(含268类不同化合物形式)所致受检者与患者27种器官/组织的吸收剂量和有效剂量;组织权重因子的变化使得分别采用99mTc、18F和131I核素进行检查的受检者有效剂量变化分别约为20%、8%和32%。结论本研究建立的数据库所包含的核素及其化合物的种类齐全,软件的用户界面友好且操作简单,适用于临床核医学诊断所致受检者与患者内照射器官剂量与有效剂量的简便估算。Objective To cope with the newest tissue weighting factors recommended by ICRP and develop a set of software for convenient estimation of the organ dose and effective dose of patients inclinical nuclear medicine. Methods Relevant electronic databases were built based on the dose conversion coefficients recommended byICRP. The organ doses were estimated using the S value method, and the effective doses were evaluated by using the newest tissue weighting factors. The software was developed by using C＋＋ programming language. Results The software can be used to estimate the absorbed doses of 27 organs/tissues and the effective doses for patients in clinical nuclear medicine applications involving a total of 47 kinds of radionuclides and 26g chemical compounds. The variance of estimated effective dose for patients undergoing diagnostics with ^99mTc,^18F and ^131I are 20% , 8% and 32% by using different versions of tissue weight factors. Conclusions The database established in this study contains a large number of radionuclides and their compounds. It can be applied for simple estimations of the organ dose and effective dose of patients in clinical nuclear medicine procedures.

关 键 词：核医学诊断 器官剂量 有效剂量 软件 

分 类 号：R144.1[医药卫生—公共卫生与预防医学]