酒精性肝病基础患者罹患戊型肝炎的临床特征  

Clinical features of hepatitis E on basis of alcoholic liver disease

作　　者：周向毅[1] 陶柏生[1] 周婷[1] 王永强[1] 黄维德[1] 

机构地区：[1]解放军第359医院肝病肿瘤科,江苏镇江212001

出　　处：《临床军医杂志》2013年第4期357-358,368,共3页Clinical Journal of Medical Officers

摘　　要：目的了解酒精性肝病基础患者罹患戊型肝炎的临床特征。方法回顾性分析2002—2011年我院收治的90例戊型肝炎患者的临床特点并进行比较,将其中有酒精性肝病基础的40例患者作为观察组,将50例无酒精性肝病基础者作为对照组。结果两组比较,观察组中发热者多(P<0.05),临床症状重(P<0.01),血清总胆红素(TB)、ALT、凝血酶原时间(PT)显著高于对照组(P<0.01),血清白蛋白(ALB)显著低于对照组(P<0.01),住院天数明显延长(P<0.01)。结论酒精性肝病基础患者罹患戊型肝炎时肝脏损害较重,症状显著,黄疸较深,易重症化,病情恢复较慢,病程较长。Objective To study the clinical characteristics of hepatitis E on the basis of alcoholic liver disease （ ALD）. Methods A retrospective analysis was clone on 90 hepatitis E patients from 2002 to 2011. The 40 ones with ALD foundation were enrolled in ALD group, and the other 50 ones without ALD foundation were enrolled in control group. Results Compared with the control group, the ALD group had more patients with fever （P 〈 0.05 ） , severer clinical symptoms （P 〈 0.01 ） , higher levels of serum to- tal bilirubin （ TB）, alanine transaminase （ALT） and prothrombin time （PT） （ P 〈 0.01 ）, lower level of serum albumin （ALB） （ P 〈 0.01 ） , and longer hospitalization duration （ P 〈 0.01 ）. Conclusion The hepatitis E patients with ALD foundation suffer from heavy hepatic injury, so their clinical symptoms are obvious and recovery is slow.

关 键 词：酒精性肝病 戊型肝炎 临床特征 

分 类 号：R512.65[医药卫生—内科学]