血塞通对全髋关节置换术围手术期红细胞免疫的影响  

Effect of sanqi panax notoginseng for erythrocyte immune during total hip replacement

作　　者：蒋剑锋[1] 魏爱淳 胡小云[1] 

机构地区：[1]江苏省海安县中医院骨科,海安226600

出　　处：《南通大学学报（医学版）》2013年第2期107-109,共3页Journal of Nantong University(Medical sciences)

基　　金：江苏省中医药科技项目(LB09116)

摘　　要：目的:探讨血塞通对全髋关节置换术围手术期红细胞免疫的影响。方法:选择40例进行全髋关节置换术(total hip replacement,THR)的患者,并随机分为血塞通组和对照组。用郭峰法测不同时间点红细胞Ⅰ型补体受体花环率(erythrocyte C3breceptor rosette,RC3bRR)、红细胞免疫复合物花环率(erythrocyte immune complex rosette,RICR)、自然肿瘤红细胞花环率(natural tumor erythrocyte rosette rate,NTERR)。结果:(1)RC3bRR、RICR、NTERR在手术前1 d两组比较差异无统计学意义(P>0.05);(2)在手术开始30 min、开始60 min、术后1 d RC3bRR、NTERR对照组低于血塞通组,RICR高于血塞通组(P<0.05);(3)血塞通组在手术开始30 min、开始60 min时RC3bRR、NTERR低于手术前1 d及手术后1 d(P<0.05),RICR高于手术前1 d及手术后1 d(P<0.05);(4)血塞通组RC3bRR、RICR及NTERR在术前1 d与术后1 d差异无统计学意义(P>0.05)。结论:THR可使红细胞免疫功能降低,血塞通有调节红细胞免疫功能的作用,在一定程度上减少THR术后深静脉血栓(deep vein thrombosis,DVT)的形成。Objective： To study the effect of sanqi panax notoginseng for erythrocyte immune during total hip replacement. Methods： 40 cases of total hip replacements were divided randomly into two groups： sanqi panax notoginseng group（S group） and unused group（U group）. They were studied by measuring different time of the red blood cell C3b receptor erythrocyte rate （RC3bRR）, immune complex rate（RICR） and natural tumour erythrocyte rosette rate（NTERR） with Guo Feng methods. Results： There were no significant differences in two groups the day before the operation. At 30 rain, 60 rain in operation and 1 day after operation, RC3bRR and NTERR in U group were obviously lower than those of S group （P〈0.05）, RICR was obviously higher than that of S group（P〈0.05）. At 30 min and 60 rain in operation and 10 rain after operation, RC3bRR and NTERR were obviously lower than those in 1 day before operation and 1 day after operation（P〈0.05）, RICR was higher than that in 1 day before operation and 1 day after operation（P〈0.05）. RC3bRR, RICR and NTERR in 1 day before operation were no significant differences from those in 1 day after operation（P〉0.05）. Conclusions： The immune function of RBC reduces after total hip replacement, sanqi panax notoginseng can regulate erythrocyte immune and reduce DVT after THR.

关 键 词：全髋关节置换术 血塞通 红细胞免疫 

分 类 号：R683.42[医药卫生—骨科学]