纵隔芯针穿刺活检64例临床病理分析  

Mediastinal lesions examined by core needle biopsy: a clinicopathologic study of 64 cases

作　　者：王齐敏[1] 吕丽[1] 孙传恕[2] 于香莉[1] 张丽[1] 王乃玉[1] 王莉芬[1] 

机构地区：[1]大连医科大学附属第二医院病理科,辽宁大连116027 [2]大连医科大学附属第二医院放射科,辽宁大连116027

出　　处：《诊断病理学杂志》2013年第4期208-211,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的总结纵隔穿刺活检组织的病理学特征、诊断和鉴别诊断要点,提高诊断的准确性。方法回顾性分析64例纵隔穿刺组织的临床表现、影像学、组织学和免疫表型特点。结果所有病例中明确诊断或倾向性诊断61例,上皮来源性肿瘤40例,淋巴瘤11例,其他肿瘤10例。其中1例弥漫性大B细胞性淋巴瘤误诊为孤立性纤维性肿瘤。结论纵隔穿刺组织的诊断需结合临床和影像学资料,同时选择适当的免疫组化方案。对于病变细胞较少、间质纤维组织增生的病例,应考虑到淋巴瘤的可能性。Objective To study the histopathological characteristics,diagnosis and differential diagnosis of mediastinal lesions examined by core needle biopsy for improvement of the diagnostic accuracy.Methods Clinical manifestations,radiological characteristics,histological characteristics and immunophenotypes were analyzed in 64 speciments of mediastinal core needle biopsy.Results 61 cases were diagnosed by core needle biopsy.Those included tumors from epithelioid cell（40 cases）,lymphoma（11 cases） and others tumors（10 cases）.A case of diffuse large B cell lymphoma was diagnosed as solitary fibrous tumor by mistake.Conclusion Microscopic assessment of tissue samples from mediastinal core needle biopsy should be made in combination with clinical and radiologic information.Immunohistochemical confirmation is utmost important to establish a definite diagnosis.When more fibrous tissue and less tumor cells are found in a case from mediastinal core needle biopsy,we should think a possible diagnosis of lymphoma.

关 键 词：纵隔疾病 穿刺活检 免疫组化 鉴别诊断 

分 类 号：F730.4[经济管理—产业经济]