小檗碱的抗动脉粥样硬化作用及其机制  

The Effect of Anti-atherosclerosis of Berberine and Its Mechanism

作　　者：贾燕珺[1] 李建军[1] 

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外医院心血管疾病国家重点实验室,北京市100037

出　　处：《中国动脉硬化杂志》2013年第4期364-368,共5页Chinese Journal of Arteriosclerosis

摘　　要：小檗碱是治疗胃肠道疾病的一种传统中药。随着研究的不断深入,新近研究结果显示小檗碱具有防治冠心病的作用。故小檗碱抗动脉粥样硬化的作用成为心血管病研究领域所注视的问题之一。本文从调脂,抗内皮损伤,抗炎症反应以及抗血栓等角度对小檗碱抗动脉粥样硬化的作用及机制加以综述。Berberine is a kind of traditional Chinese medicine of treating gastrointestinal diseases. With the deep- ening of the research, it has been found that berberine has an important role in the prevention of coronary heart disease. Therefore, the study of berberine has become one of the focuses in research of atherosclerosis. The effect of anti-athero- sclerosis of berberine and its mechanism were reviewed from regulating lipid, resistant endothelial injury, anti-inflammatory response and antithrombotic in this article.

关 键 词：小檗碱 抗动脉粥样硬化 

分 类 号：R5[医药卫生—内科学]