重度吸入性损伤的呼吸支持与治疗  

Respiratory support and treatment of severe inhalation injury

作　　者：郭光华[1] 

机构地区：[1]南昌大学第一附属医院烧伤科,南昌330006

出　　处：《中华烧伤杂志》2013年第2期134-138,共5页Chinese Journal of Burns

基　　金：国家自然科学基金（30960400）;高等学校博士学科点专项科研基金（20093601110005）;江西省科技厅支撑计划（2010BSAl0300）

摘　　要：在火灾受害者当中，吸入性损伤具有很高的发生率和病死率，特别是在密闭环境中，烟雾所致吸入性损伤为致死的最主要原因之一^[1]。吸入性损伤的实质是急性肺损伤（ALI），两者有相似的病理生理改变和临床表现，但不能完全等同。Although the study of inhalation injury is deepening gradually, its clinical treatment is still difficuh, and its mortality rate remains high due to the complicated pathophysiologic characteristics. This article reviews the recent progress in research and treatment of inhalation injury, acute lung injury, and acute respiratory distress syndrome at home and abroad, focusing on the effect of mechanical ventilation models, including the non-invasive ventilation, lung protective ventilation, liquid ventilation, high fi＇equency ventilation, on respiratory support in early stage of inhalation injury. The effects of mectications for inhalation injury are summarized, and the prospect of stem cell therapy for inhalation injury is also discussed.

关 键 词：烧伤 吸入性 高频通气 干细胞 肺保护性通气 

分 类 号：R563[医药卫生—呼吸系统]