触觉刺激三叉神经上颌支面部支配区的功能性MRI研究  

Brain Activity and Facial Tactile in Trigeminal Maxillary Division: An Functional MRI Study

作　　者：李家[1,2] 刘洪臣[2] 李科[3] 金真[3] 朱霞[1] 

机构地区：[1]同济大学口腔医学院生物医学及转化实验室,上海202072 [2]解放军总医院口腔医学院研究所,北京100083 [3]解放军306医院放射科,北京100101

出　　处：《口腔颌面外科杂志》2013年第2期98-100,共3页Journal of Oral and Maxillofacial Surgery

基　　金：国家自然科学基金资助项目(30772450)

摘　　要：目的:观察触觉刺激三叉神经上颌支(简称V2)面部支配区引起的大脑中枢反应区。方法 :选取8名健康志愿者,用棉签刺激右侧面部三叉神经上颌支的支配区,采用触觉刺激减静息的组块设计方法,采集全脑血氧水平依赖对比的功能性MRI扫描数据。结果:脑激活区为左侧初级躯体感觉皮质(BA3)、岛叶/SII、BA22、BA45,右侧BA40、BA9、BA38、BA41。结论:对侧初级躯体感觉皮质、岛叶/SII和颞上回,同侧中央后回、颞下回和颞横回及双侧前额皮质是面部V2区触觉刺激激活的脑部功能区。Objective： To evaluate the brain cortical response to facial tactile in maxillary trigeminal division. Methods： 8 healthy volunteers participated in the study. Cotton-tipped swab stimuli was applied to right side of face in maxillary trigeminal division, and block designed BOLD functional MRI scan covering the whole brain was carried out. Results： Increased BOLD signals during tactile stimulation were found in left SI （BA3）, insula/SII, Brodman＇s area 22,45, and right Brodman＇s area 40,9,38,41. Conclusion：Tactile stimuli activated contra]ateral primary, secondary somatosensory cortex, superior temporal gyms, ipsilateral postcentral gyms , inferior temporal gyms, transverse temporal gyms, bilateral prefrontal cortex .

关 键 词：颌面部 触觉 大脑皮质 功能性磁共振成像(fMRI) 

分 类 号：R445.2[医药卫生—影像医学与核医学]