呼吸窘迫综合征早产儿宫外生长受限及早期营养干预  

Extrauterine growth restriction and early nutrition support of infants with respiratory distress syndrome

作　　者：崔凤静[1] 单若冰 

机构地区：[1]青岛大学医学院新生儿科,266001 [2]青岛妇女儿童医院,266001

出　　处：《中国小儿急救医学》2013年第2期135-139,共5页Chinese Pediatric Emergency Medicine

摘　　要：目的 评价患有新生儿呼吸窘迫综合征（respiratory distress syndrome,RDS）的早产儿出生时宫内生长受限（intrauterine growth restriction,IUGR）和出院时宫外生长受限（extrauterine growth restriction,EUGR）的发生率,并分析其对早期营养支持的影响.方法 收集新生儿重症监护室符合入选标准的70例RDS早产儿的临床资料,根据出院时体重是否存在EUGR,分为EUGR组（48例）和非EUGR组（22例）,比较两组患儿基本情况、围生期因素、住院期间营养摄入状况、治疗措施及合并症方面的差异.结果 以体重评价,70例RDS早产儿IUGR与EUGR的发生率分别为12.86％ （9/70）和60.00％ （42/70）；两组出生体重[（1 666.10 ±440.16）g vs（2 108.20±552.81）g]、出生头围[（28.81±2.65） cm vs （30.48±2.39） cm]、多胎妊娠例数（16例vs 3例）、剖宫产例数（29例vs 7例）差异有统计学意义（P＜0.05）；在出生胎龄、住院期间营养摄入、呼吸机支持及合并症方面两组之间差异无统计学意义（P＞0.05）.结论 RDS早产儿的EUGR与存在IUGR、多胎妊娠、剖宫产、出生体重低、出生头围小有关,住院短时间的营养干预尚不能改善RDS早产儿的EURG.Objective To assess the incidences of intrauterine growth restriction （IUGR） and extrauterine growth restriction（EUGR） in premature infants with respiratory distress syndrome （RDS） and early nutritional efficiency on EUGR.Methods Data of 70 infants with RDS admitted in neonatal intensive care unit were reviewed.According to the weight when a premature infant was discharged,all subjects were divided into EUGR group（48 cases） and non-EUGR group（22 cases）.The difference of two groups in terms of basic situation,peripartum factors,nutritional support,treatment measures and complications were compared.Results Assessing by weight,the incidence of IUGR and EUGR was 12.86% （9/70）and 60.00% （42/70）respectively.The differences in birth weight [（1 666.10 ±440.16） g vs （2 108.20 ±552.81） g],head circumference at birth [（28.81 ± 2.65） cm vs （30.48 ± 2.39） cm],IUGR,multiple pregnancy （16 cases vs 3 cases）,cesarean delivery （29 cases vs 7 cases） were considered statistically significant （P 〈 0.05）,and there were no stastitically significant difference in gestational age,nutritional support,mechanical ventilation and complications （P 〉 0.05）.Conclusion The EUGR is related with IUGR,multiple pregnancy,cesarean delivery,low birthweight,low birth head circumference.The short time nutrition interventions can＇t improve EUGR in RDS.

关 键 词：新生儿呼吸窘迫综合征 宫外生长受限 早期营养 早产儿 

分 类 号：R722.6[医药卫生—儿科]